Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 10/20 | 0.44 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.43 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP1 | P63208 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | SUV39H2 | Q9H5I1 | 3/20 | 0.37 |
| ▸ | SMO | Q99835 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31144088 | 1.00 | RET (0.44) | RETEIF2AK4CKS1BSKP1SKP2 | |
| SCHEMBL28715860 | 0.89 | RET (0.52) | RETEIF2AK4CKS1BSKP1SKP2 | |
| SCHEMBL31144131 | 0.88 | RET (0.45) | RETEIF2AK4CKS1BSKP1SKP2 | |
| SCHEMBL31143957 | 0.81 | RET (0.54) | RETEIF2AK4SYK | |
| SCHEMBL28716631 | 0.81 | RET (0.54) | RETEIF2AK4SYK | |
| SCHEMBL31144083 | 0.79 | RET (0.51) | RETSYK | |
| SCHEMBL20070053 | 0.79 | RET (0.51) | RETEIF2AK4CKS1BSKP1SKP2 | |
| SCHEMBL28703228 | 0.76 | RET (0.49) | RETSYK | |
| SCHEMBL31143986 | 0.76 | RET (0.47) | RETJAK3 | |
| SCHEMBL31143925 | 0.73 | RET (0.51) | RETEIF2AK4CKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461670-A | Novel compounds as inhibitors of rearrangement kinase during transfection | 南京天印健华医药科技有限公司 | 2021-10-01 | — | — | CN | disclosed |