Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 18/20 | 0.54 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31143957 | 1.00 | RET (0.54) | RETEIF2AK4SYK | |
| SCHEMBL28715860 | 0.88 | RET (0.52) | RETEIF2AK4SYK | |
| SCHEMBL31144083 | 0.81 | RET (0.51) | RETSYK | |
| SCHEMBL28713480 | 0.81 | RET (0.44) | RETEIF2AK4SYK | |
| SCHEMBL31144088 | 0.81 | RET (0.44) | RETEIF2AK4SYK | |
| SCHEMBL28703228 | 0.79 | RET (0.49) | RETSYK | |
| SCHEMBL28462137 | 0.78 | RET (0.54) | RET | |
| SCHEMBL31071888 | 0.78 | RET (0.54) | RET | |
| SCHEMBL31071776 | 0.77 | RET (0.55) | RET | |
| SCHEMBL28709581 | 0.76 | RET (0.55) | RETEIF2AK4SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461670-A | Novel compounds as inhibitors of rearrangement kinase during transfection | 南京天印健华医药科技有限公司 | 2021-10-01 | — | — | CN | disclosed |