Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL286793 | 0.89 | KMT2A (0.37) | CHRM5CHRM3KMT2AMEN1KDM4E | |
| SCHEMBL658611 | 0.68 | CA12 (0.32) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL27605542 | 0.65 | CHRM5 (0.43) | CHRM5CHRM3KMT2AMEN1KDM4E | |
| SCHEMBL7800030 | 0.65 | KMT2A (0.39) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL5534141 | 0.63 | CHRM5 (0.41) | CHRM5CHRM3KMT2AMEN1KDM4E | |
| SCHEMBL15386866 | 0.62 | KMT2A (0.56) | CHRM5CHRM3KMT2AMEN1KDM4E | |
| SCHEMBL27573159 | 0.61 | KMT2A (0.37) | CHRM5CHRM3KMT2AMEN1KDM4E | |
| SCHEMBL23464917 | 0.60 | CHRM5 (0.75) | CHRM5CHRM3KMT2AMEN1KDM4E | |
| SCHEMBL24170865 | 0.60 | ALOX5 (0.39) | KMT2AALDH1A1L3MBTL1NPC1GAA | |
| SCHEMBL7721235 | 0.59 | CHRM5 (0.72) | CHRM5CHRM3KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427432-A2 | NOVEL HETEROCYCLIC COMPOUNDS | Torrent Pharmaceuticals Limited (IN) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128528-A2 | NOVEL HETEROCYCLIC COMPOUNDS | TORRENT PHARMACEUTICALS LIMITED (IN) | 2010-11-11 | — | — | WO | disclosed |