Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 11/20 | 0.46 |
| ▸ | GRM5 | P41594 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2779409 | 0.78 | RIOK2 (0.43) | NR3C2SMN1; SMN2NPC1TP53RAB9A | |
| SCHEMBL29601179 | 0.78 | SMN1; SMN2 (0.61) | SMN1; SMN2NPC1TP53RAB9AMAPT | |
| SCHEMBL28712383 | 0.78 | PHGDH (0.48) | NR3C2SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL2780621 | 0.78 | SMN1; SMN2 (0.61) | SMN1; SMN2NPC1TP53RAB9AMAPT | |
| SCHEMBL27039726 | 0.77 | PHGDH (0.51) | NR3C2GRM5RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL31629775 | 0.76 | NPC1 (0.50) | NR3C2GRM5JAK2SMN1; SMN2NPC1 | |
| SCHEMBL435402 | 0.76 | NPC1 (0.50) | NR3C2GRM5JAK2SMN1; SMN2NPC1 | |
| SCHEMBL6181374 | 0.75 | NR3C2 (0.48) | NR3C2SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL29078745 | 0.75 | ROCK1 (0.44) | NR3C2SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL19890689 | 0.74 | L3MBTL1 (0.55) | JAK2SMN1; SMN2NPC1TP53RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114249702-B | N-aryl- [2,4 '-dithiazole ] -2' -amine compound and preparation and application thereof | 沈阳药科大学 | 2023-09-05 | — | — | CN | disclosed |
| CN-114249702-A | N-aryl- [2,4 '-bithiazole ] -2' -amine compound and preparation and application thereof | 沈阳药科大学 | 2022-03-29 | — | — | CN | disclosed |