Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 5/20 | 0.43 |
| ▸ | F2R | P25116 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28495217 | 0.81 | HDAC6 (0.70) | HDAC6HDAC1NOTUMKDM4E | |
| SCHEMBL27643302 | 0.72 | HPGD (0.61) | HDAC6HDAC1LMNAPTPN1KDM4E | |
| SCHEMBL28504784 | 0.68 | HDAC1 (0.69) | HDAC6HDAC1NOTUMLMNASMN1; SMN2 | |
| SCHEMBL27690465 | 0.67 | GAA (0.61) | HDAC6HDAC1LMNASMN1; SMN2 | |
| SCHEMBL28509075 | 0.65 | HDAC6 (1.00) | HDAC6HDAC1KDM4ESMN1; SMN2 | |
| SCHEMBL28502726 | 0.62 | HDAC1 (0.70) | HDAC6HDAC1SMN1; SMN2 | |
| SCHEMBL19116540 | 0.62 | PTPN1 (0.59) | F2RLMNAPTPN1KDM4EHPGD | |
| SCHEMBL28709589 | 0.61 | HDAC6 (0.69) | HDAC6HDAC1KDM4ESMN1; SMN2 | |
| SCHEMBL28495853 | 0.61 | HDAC6 (0.70) | HDAC6HDAC1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL27690463 | 0.60 | ALDH1A1 (0.57) | KDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111943892-B | Histone deacetylase subtype inhibitor thioacetylarylamine compound and application thereof | 上海中泽医药科技有限公司 | 2022-04-05 | — | — | CN | claimed |