Biphenyl

Biphenyl

SCHEMBL28720282

Oc1ccccc1.Oc1ccccc1.Oc1ccccc1.Oc1ccccc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 2/20 0.81
MMP3 P08254 1/20 0.81
CA12 O43570 1/20 0.79
CA1 P00915 1/20 0.79
CA2 P00918 1/20 0.79
GLA P06280 1/20 0.79
CA3 P07451 1/20 0.79
CA4 P22748 1/20 0.79
CA9 Q16790 1/20 0.79
TDP1 Q9NUW8 1/20 0.79
CA14 Q9ULX7 1/20 0.79
ALDH1A1 P00352 3/20 0.64
HSD17B1 P14061 3/20 0.57
HSD17B2 P37059 3/20 0.57
ESR1 P03372 5/20 0.56
ESR2 Q92731 3/20 0.56
MEN1 O00255 4/20 0.55
KMT2A Q03164 4/20 0.55
CYP3A4 P08684 1/20 0.55
CYP2C9 P11712 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL208602 1.00 BCL2L1 (0.81) BCL2L1MMP3CA12CA1CA2
Biphenyl SCHEMBL2236704 1.00 BCL2L1 (0.81) BCL2L1MMP3CA12CA1CA2
Biphenyl SCHEMBL25212052 1.00 BCL2L1 (0.81) BCL2L1MMP3CA12CA1CA2
Biphenyl SCHEMBL1764506 0.97 BCL2L1 (0.77) BCL2L1MMP3CA12CA1CA2
Biphenyl SCHEMBL28837352 0.97 BCL2L1 (0.77) BCL2L1MMP3CA12CA1CA2
Tannin Pyrogallol SCHEMBL28132375 0.97 MMP3 (0.88) BCL2L1MMP3CA12CA1CA2
Biphenyl SCHEMBL27741402 0.97 BCL2L1 (0.77) BCL2L1MMP3CA12CA1CA2
Biphenyl SCHEMBL11152404 0.97 BCL2L1 (0.77) BCL2L1MMP3CA12CA1CA2
Biphenyl SCHEMBL28985955 0.97 BCL2L1 (0.77) BCL2L1MMP3CA12CA1CA2
Biphenyl SCHEMBL28204518 0.97 BCL2L1 (0.77) BCL2L1MMP3CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114349954-B Phthalonitrile-terminated polyaryl ether nitrile containing methylene/methylene, crosslinked cured modified polyaryl ether nitrile and preparation method thereof 四川大学 2023-11-21 CN disclosed
CN-114349954-A Phenylene/methine-containing phthalonitrile-terminated polyarylene ether nitrile, crosslinked cured modified polyarylene ether nitrile and preparation method thereof 四川大学 2022-04-15 CN disclosed