SCHEMBL28720286

SCHEMBL28720286

CN(C)Cc1ccc(-c2ccc(O)cc2)cc1

nearest known ligand 0.77

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 5/20 0.77
TAAR1 Q96RJ0 2/20 0.65
ESR1 P03372 4/20 0.50
ESR2 Q92731 3/20 0.50
ALDH1A1 P00352 1/20 0.50
TSHR P16473 1/20 0.50
NOS3 P29474 1/20 0.46
NOS1 P29475 1/20 0.46
NOS2 P35228 1/20 0.46
BRD4 O60885 1/20 0.45
BRD9 Q9H8M2 1/20 0.45
TTK P33981 1/20 0.45
AURKB Q96GD4 1/20 0.45
INCENP Q9NQS7 1/20 0.45
MCHR1 Q99705 1/20 0.44
LTB4R2 Q9NPC1 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL116611 0.93 HRH3 (0.64) HRH3TAAR1ESR1ESR2ALDH1A1
SCHEMBL19206134 0.93 HRH3 (0.64) HRH3TAAR1ESR1ESR2ALDH1A1
SCHEMBL28611070 0.91 HRH3 (0.61) HRH3TAAR1ESR1ESR2ALDH1A1
Hydrochloric Acid SCHEMBL27583166 0.91 HRH3 (0.61) HRH3TAAR1ESR1ESR2ALDH1A1
SCHEMBL28314964 0.88 HRH3 (0.58) HRH3TAAR1ESR1ESR2ALDH1A1
SCHEMBL12679031 0.88 HRH3 (1.00) HRH3TAAR1ALDH1A1TSHRNOS3
Butane SCHEMBL27686347 0.86 HRH3 (0.56) HRH3TAAR1ESR1ESR2ALDH1A1
SCHEMBL28271160 0.84 HRH3 (0.54) HRH3TAAR1ESR1ESR2ALDH1A1
SCHEMBL18664588 0.83 HRH3 (0.52) HRH3TAAR1ESR1ESR2ALDH1A1
SCHEMBL12960335 0.82 HRH3 (0.77) HRH3TAAR1ALDH1A1TSHRNOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110121515-B Fluorine-containing active energy ray-curable resin, surfactant, active energy ray-curable resin composition, and cured coating film DIC株式会社 2022-03-11 CN disclosed