Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 1.00 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.52 |
| ▸ | TTK | P33981 | 1/20 | 0.52 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.52 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.52 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.48 |
| ▸ | NOS3 | P29474 | 1/20 | 0.48 |
| ▸ | NOS1 | P29475 | 1/20 | 0.48 |
| ▸ | NOS2 | P35228 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.46 |
| ▸ | PYCR1 | P32322 | 2/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL659509 | 0.91 | HRH3 (0.82) | HRH3TAAR1ALDH1A1TSHRBRD4 | |
| SCHEMBL23512760 | 0.90 | HRH3 (0.81) | HRH3TAAR1ALDH1A1TSHRBRD4 | |
| SCHEMBL260357 | 0.90 | HRH3 (0.81) | HRH3TAAR1ALDH1A1TSHRBRD4 | |
| SCHEMBL5915632 | 0.90 | TAAR1 (1.00) | HRH3TAAR1ALDH1A1TSHRPYCR1 | |
| SCHEMBL4728405 | 0.88 | HRH3 (0.77) | HRH3TAAR1ALDH1A1TSHRBRD4 | |
| SCHEMBL2056269 | 0.88 | HRH3 (0.77) | HRH3TAAR1ALDH1A1TSHRBRD4 | |
| SCHEMBL12960340 | 0.88 | HRH3 (0.77) | HRH3TAAR1ALDH1A1TSHRBRD4 | |
| SCHEMBL796104 | 0.88 | HRH3 (0.77) | HRH3TAAR1ALDH1A1TSHRBRD4 | |
| SCHEMBL12960335 | 0.88 | HRH3 (0.77) | HRH3TAAR1ALDH1A1TSHRBRD4 | |
| SCHEMBL27825225 | 0.88 | HRH3 (0.77) | HRH3TAAR1ALDH1A1TSHRBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3129102-B1 | IODONIUM ANALOGS AS INHIBITORS OF NADPH OXIDASES AND OTHER FLAVIN DEHYDROGENASES; FORMULATIONS THEREOF; AND USES THEREOF | US HEALTH (US) | 2025-06-18 | — | — | EP | disclosed |
| US-20230371289-A1 | IMAGING DEVICE | PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) | 2023-11-16 | — | — | US | disclosed |
| US-10738047-B2 | Iodonium analogs as inhibitors of NADPH oxidases and other flavin dehydrogenases; formulations thereof; and uses thereof | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH (US) | 2020-08-11 | — | — | US | disclosed |
| US-20190048001-A1 | IODONIUM ANALOGS AS INHIBITORS OF NADPH OXIDASES AND OTHER FLAVIN DEHYDROGENASES; FORMULATIONS THEREOF; AND USES THEREOF | THE US SECRETARY DEPARTMENT OF HEALTH (US) | 2019-02-14 | — | — | US | disclosed |
| US-10131659-B2 | Iodonium analogs as inhibitors of NADPH oxidases and other flavin dehydrogenases; formulations thereof; and uses thereof | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2018-11-20 | — | — | US | disclosed |
| EP-3129102-A1 | IODONIUM ANALOGS AS INHIBITORS OF NADPH OXIDASES AND OTHER FLAVIN DEHYDROGENASES; FORMULATIONS THEREOF; AND USES THEREOF | The U.S.A. As Represented By The Secretary, Department Of Health And Human Services (US) | 2017-02-15 | — | — | EP | disclosed |
| US-20170029424-A1 | IODONIUM ANALOGS AS INHIBITORS OF NADPH OXIDASES AND OTHER FLAVIN DEHYDROGENASES; FORMULATIONS THEREOF; AND USES THEREOF | THE US SECRETARY DEPT OF HEALTH (US) | 2017-02-02 | — | — | US | disclosed |
| WO-2015157145-A1 | IODONIUM ANALOGS AS INHIBITORS OF NADPH OXIDASES AND OTHER FLAVIN DEHYDROGENASES; FORMULATIONS THEREOF; AND USES THEREOF | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2015-10-15 | — | — | WO | disclosed |
| US-20120321348-A1 | IMAGE BEARING DRUM, IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND PROCESS CARTRIDGE | RICOH COMPANY, LTD. (JP) | 2012-12-20 | — | — | US | disclosed |
| US-20120321348-A1 | IMAGE BEARING DRUM, IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND PROCESS CARTRIDGE | RICOH COMPANY, LTD. (JP) | 2012-12-20 | — | — | US | disclosed |
| US-8273513-B2 | Image forming apparatus, process cartridge, and image bearing member | RICOH COMPANY, LIMITED (JP) | 2012-09-25 | — | — | US | disclosed |
| US-8273513-B2 | Image forming apparatus, process cartridge, and image bearing member | RICOH COMPANY, LIMITED (JP) | 2012-09-25 | — | — | US | disclosed |
| US-20100330475-A1 | IMAGE FORMING APPARATUS, PROCESS CARTRIDGE, AND IMAGE BEARING MEMBER | RICOH COMPANY LIMITED (JP) | 2010-12-30 | — | — | US | disclosed |
| US-20100330475-A1 | IMAGE FORMING APPARATUS, PROCESS CARTRIDGE, AND IMAGE BEARING MEMBER | RICOH COMPANY LIMITED (JP) | 2010-12-30 | — | — | US | disclosed |
| US-20090180788-A1 | Image forming apparatus, and image forming method | RICOH COMPANY, LTD. (JP) | 2009-07-16 | — | — | US | disclosed |
| US-20090180788-A1 | Image forming apparatus, and image forming method | RICOH COMPANY, LTD. (JP) | 2009-07-16 | — | — | US | disclosed |
| US-20080227007-A1 | Image forming apparatus and process cartridge | RICOH COMPANY, LTD. | 2008-09-18 | — | — | US | disclosed |
| US-20080227007-A1 | Image forming apparatus and process cartridge | RICOH COMPANY, LTD. | 2008-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190048001-A1 | IODONIUM ANALOGS AS INHIBITORS OF NADPH OXIDASES AND OTHER FLAVIN DEHYDROGENASES; FORMULATIONS THEREOF; AND USES THEREOF | NOX5, CYBB, NOX1 | HRH3 3739/4885TAAR1 2446/4885ALDH1A1 108/4885 |
| US-10131659-B2 | Iodonium analogs as inhibitors of NADPH oxidases and other flavin dehydrogenases; formulations thereof; and uses thereof | NOX5, CYBB, NOX1 | HRH3 3739/4885TAAR1 2446/4885ALDH1A1 108/4885 |
| US-20170029424-A1 | IODONIUM ANALOGS AS INHIBITORS OF NADPH OXIDASES AND OTHER FLAVIN DEHYDROGENASES; FORMULATIONS THEREOF; AND USES THEREOF | NOX5, CYBB, NOX1 | HRH3 3739/4885TAAR1 2446/4885ALDH1A1 108/4885 |
| US-10738047-B2 | Iodonium analogs as inhibitors of NADPH oxidases and other flavin dehydrogenases; formulations thereof; and uses thereof | NOX5, CYBB, NOX1 | HRH3 3739/4885TAAR1 2446/4885ALDH1A1 108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.