Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATF4 | P18848 | 10/20 | 0.66 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23920295 | 0.86 | ATF4 (0.72) | ATF4FAAHBCHEACHEALDH1A1 | |
| SCHEMBL28724353 | 0.85 | ATF4 (0.70) | ATF4 | |
| SCHEMBL28577681 | 0.84 | ATF4 (0.69) | ATF4FAAHBCHEACHEALDH1A1 | |
| SCHEMBL21819532 | 0.83 | ATF4 (0.75) | ATF4FAAHBCHEACHEALDH1A1 | |
| SCHEMBL22777707 | 0.81 | ATF4 (0.67) | ATF4FAAHBCHEACHEALDH1A1 | |
| SCHEMBL21819632 | 0.80 | ATF4 (1.00) | ATF4ALDH1A1 | |
| SCHEMBL24998181 | 0.80 | ATF4 (0.73) | ATF4FAAHBCHEACHEALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL22777533 | 0.79 | ATF4 (0.62) | ATF4FAAHBCHEACHEALDH1A1 | |
| SCHEMBL21819687 | 0.78 | ATF4 (0.86) | ATF4FAAHBCHEACHEALDH1A1 | |
| SCHEMBL24998180 | 0.77 | ATF4 (0.66) | ATF4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206829-A | Integrated stress response pathway inhibitors | 普拉西斯生物技术有限责任公司 | 2022-03-18 | — | — | CN | disclosed |