Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 13/20 | 0.52 |
| ▸ | ACACA | Q13085 | 9/20 | 0.52 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.49 |
| ▸ | ATF4 | P18848 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23920476 | 1.00 | ACACB (0.52) | ACACBACACAPBKATF4HTR7 | |
| SCHEMBL29526791 | 1.00 | ACACB (0.52) | ACACBACACAPBKATF4HTR7 | |
| SCHEMBL28516457 | 0.89 | ATF4 (0.49) | ATF4HTR7HPGDS | |
| SCHEMBL29354666 | 0.89 | ATF4 (0.49) | ATF4HTR7HPGDS | |
| SCHEMBL24225655 | 0.89 | ATF4 (0.49) | ATF4HTR7HPGDS | |
| SCHEMBL22373872 | 0.87 | ACACB (0.47) | ACACBACACAPBKATF4 | |
| SCHEMBL23920506 | 0.85 | ATF4 (0.51) | ACACBACACAATF4 | |
| SCHEMBL22777602 | 0.85 | ATF4 (0.51) | ATF4HTR7MAPK14 | |
| SCHEMBL22777611 | 0.82 | ATF4 (0.48) | ATF4HTR7 | |
| SCHEMBL22777610 | 0.82 | ATF4 (0.48) | ATF4HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206829-A | Integrated stress response pathway inhibitors | 普拉西斯生物技术有限责任公司 | 2022-03-18 | — | — | CN | disclosed |