Known targets — ChEMBL curated mechanism
FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.31 |
| ▸ | NMT1 | P30419 | 1/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL83682 | 0.93 | POLB (0.38) | POLBSMN1; SMN2HSD17B10ALDH1A1MEN1 | |
| SCHEMBL28790654 | 0.93 | POLB (0.38) | POLBSMN1; SMN2HSD17B10ALDH1A1MEN1 | |
| Ammonia Solution, Strong SCHEMBL28018788 | 0.91 | POLB (0.37) | POLBSMN1; SMN2HSD17B10ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL28378505 | 0.91 | SMN1; SMN2 (0.37) | POLBSMN1; SMN2HSD17B10ALDH1A1MEN1 | |
| Alcohol SCHEMBL28979374 | 0.91 | POLB (0.37) | POLBSMN1; SMN2HSD17B10ALDH1A1MEN1 | |
| SCHEMBL6010040 | 0.91 | POLB (0.37) | POLBSMN1; SMN2HSD17B10ALDH1A1MEN1 | |
| Potassium Ion SCHEMBL27651535 | 0.90 | POLB (0.36) | POLBSMN1; SMN2HSD17B10ALDH1A1MEN1 | |
| Water SCHEMBL27783793 | 0.90 | POLB (0.36) | POLBSMN1; SMN2HSD17B10ALDH1A1MEN1 | |
| Potassium Ion SCHEMBL28463218 | 0.86 | POLB (0.36) | POLBSMN1; SMN2HSD17B10ALDH1A1MEN1 | |
| SCHEMBL3655480 | 0.86 | POLB (0.36) | POLBSMN1; SMN2HSD17B10ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114306240-A | Gemcitabine or liposome of salt thereof, preparation method and application thereof | 四川科伦药物研究院有限公司 | 2022-04-12 | — | — | CN | claimed |
| CN-114306240-A | Gemcitabine or liposome of salt thereof, preparation method and application thereof | 四川科伦药物研究院有限公司 | 2022-04-12 | — | — | CN | disclosed |