Known targets — ChEMBL curated mechanism
FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28790654 | 1.00 | POLB (0.38) | POLBSMN1; SMN2HSD17B10ALDH1A1KMT2A | |
| Alcohol SCHEMBL28979374 | 0.98 | POLB (0.37) | POLBSMN1; SMN2HSD17B10ALDH1A1KMT2A | |
| Ammonia Solution, Strong SCHEMBL28018788 | 0.98 | POLB (0.37) | POLBSMN1; SMN2HSD17B10ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL28378505 | 0.98 | SMN1; SMN2 (0.37) | POLBSMN1; SMN2HSD17B10ALDH1A1KMT2A | |
| SCHEMBL6010040 | 0.98 | POLB (0.37) | POLBSMN1; SMN2HSD17B10ALDH1A1KMT2A | |
| Water SCHEMBL27783793 | 0.96 | POLB (0.36) | POLBSMN1; SMN2HSD17B10ALDH1A1KMT2A | |
| Potassium Ion SCHEMBL27651535 | 0.96 | POLB (0.36) | POLBSMN1; SMN2HSD17B10ALDH1A1KMT2A | |
| Sulfuric Acid SCHEMBL28720448 | 0.93 | POLB (0.34) | POLBSMN1; SMN2HSD17B10ALDH1A1KMT2A | |
| SCHEMBL108942 | 0.92 | ALDH1A1 (0.36) | POLBSMN1; SMN2HSD17B10ALDH1A1KMT2A | |
| Sulfuric Acid SCHEMBL29010960 | 0.90 | POLB (0.39) | POLBSMN1; SMN2HSD17B10ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 10708 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122081421-A | Method for preparing chiral beta-trifluoromethyl alcohol compound by adopting non-heme iron enzyme BsQueD or mutant thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122080428-A | Metal organic framework material for detecting copper ions and preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122057028-A | Mitochondria targeting triple-response nano platform and preparation method and application thereof | 暨南大学 | 2026-05-19 | — | — | CN | claimed |
| CN-122060840-A | Thromboelastography heparin detection reagent and application thereof | 北京睿瑧生物技术有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-118021703-B | Vitamin E moisturizing skin lotion added with peony fresh flower stock solution and preparation method thereof | 北京迷奇生物科技有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122060665-A | Construction method of children Crohn's disease intestinal organoids | 浙江大学 | 2026-05-19 | — | — | CN | claimed |
| CN-122042985-A | Thromboelastography quality control product, preparation method and application thereof in preparation of blood coagulation detection product, blood coagulation detection product and blood coagulation detection method | 山东新华医疗器械股份有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122031412-A | High-stability elastase enteric capsule and preparation method thereof | 山东希力药业有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122038171-A | In-vitro culture method and compound culture medium for segmented filamentous fungi | 江西农业大学 | 2026-05-15 | — | — | CN | claimed |
| CN-116687774-B | Water-soluble composition containing ferulic acid and whitening and soothing frozen film containing composition | 广州环亚化妆品科技股份有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-1154658-C | Method for purifying glycoproteins such as erythropoietin | �����ɷ� | 2004-06-23 | — | — | CN | claimed |
| CN-1154717-C | Improved immortalized human skin cell lines and novel serum-free medium useful for prodn. thereof | �Ʒ� | 2004-06-23 | — | — | CN | claimed |
| US-20030026831-A1 | Anionic liposomes for delivery of bioactive agents | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2003-02-06 | — | — | US | claimed |
| CN-2531391-Y | Enzyme immunoassay kit for combined detection TORCH specificity antibody | WANG TAO (CN) | 2003-01-15 | — | — | CN | claimed |
| US-6448251-B1 | FATTY ACID ESTER OF HEPES FOR TOPICAL TREATMENT OF DERMATITIS | HAWKEYE-JENSEN, INC. | 2002-09-10 | — | — | US | claimed |
| US-6114337-A | Zwitteronic-fatty acid compounds having anti-inflammatory properties | PUGLIESE PETER T (US) | 2000-09-05 | — | — | US | claimed |
| US-5792330-A | Lanthanide metal cations for concurrent detection and separation in capillary electrophoresis | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1998-08-11 | — | — | US | claimed |
| CN-1181759-A | Process for the purification of glycoproteins like erythropoietin | LEPETIT SPA (IT) | 1998-05-13 | — | — | CN | claimed |
| EP-0726467-B1 | Method of calibration of a pH sensor | AVL MEDICAL INSTR AG (CH) | 1998-02-18 | — | — | EP | claimed |
| US-5658451-A | CONTACTING ION-PERMEABLE, HYDROPHILIC POLYMER LAYER WITH AQUEOUS SOLUTION CONTAINING STABLE WEAK ACID OR BASE AS BUFFER, DISPLACING OR REPLACING SOLUTION BY GASEOUS CALIBRATING MEDIUM, ALLOWING REACTION WITH ACID OR BASE | AVL MEDICAL INSTRUMENTS AG (CH) | 1997-08-19 | — | — | US | claimed |