Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 4/20 | 0.37 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22321483 | 0.83 | MEN1 (0.44) | CYP3A4IMPDH2PTPN1KDM4ECYP1A2 | |
| SCHEMBL14486685 | 0.82 | KMT2A (0.42) | CYP3A4KCNA3GAAMAPK1PTPN1 | |
| SCHEMBL9752570 | 0.79 | CYP3A4 (0.44) | CYP3A4KCNA3MAPK1PKMPTPN1 | |
| SCHEMBL11121530 | 0.79 | CYP3A4 (0.44) | CYP3A4KCNA3MAPK1PKMPTPN1 | |
| SCHEMBL15214023 | 0.76 | CYP3A4 (0.40) | CYP3A4IMPDH2KCNA3MAPK1 | |
| SCHEMBL11440464 | 0.74 | KMT2A (0.41) | CYP3A4KCNA3GAAMAPK1PTPN1 | |
| SCHEMBL6727338 | 0.74 | TAS1R3 (0.47) | CYP3A4NPC1CYP1A2KMT2A | |
| SCHEMBL29042640 | 0.72 | CYP3A4 (0.39) | CYP3A4MAPK1PKMKDM4ECYP1A2 | |
| SCHEMBL13355621 | 0.72 | MEN1 (0.50) | CYP3A4IMPDH2GAAMAPK1KDM4E | |
| SCHEMBL16049988 | 0.72 | MEN1 (0.46) | CYP3A4IMPDH2GAAMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110139865-B | FGFR inhibitors | 石药集团中奇制药技术（石家庄）有限公司 | 2022-02-18 | — | — | CN | disclosed |