Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PRNP | P04156 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL593258 | 0.89 | DAO (0.60) | GSK3BLMNATSHRMAPTL3MBTL1 | |
| SCHEMBL11160378 | 0.87 | F2 (0.58) | GSK3BLMNATSHRMAPTL3MBTL1 | |
| SCHEMBL14495742 | 0.87 | GSK3B (0.55) | GSK3BLMNATSHRMAPTL3MBTL1 | |
| SCHEMBL5460390 | 0.87 | GSK3B (0.61) | GSK3BLMNATSHRMAPTL3MBTL1 | |
| SCHEMBL1356959 | 0.86 | LMNA (0.70) | GSK3BLMNATSHRMAPTL3MBTL1 | |
| SCHEMBL20239452 | 0.84 | — | — | |
| SCHEMBL3351 | 0.84 | — | — | |
| SCHEMBL12569052 | 0.84 | LMNA (0.68) | GSK3BLMNATSHRMAPTL3MBTL1 | |
| SCHEMBL8575623 | 0.84 | LMNA (0.68) | GSK3BLMNATSHRMAPTL3MBTL1 | |
| SCHEMBL6395252 | 0.83 | KDM4E (0.55) | GSK3BLMNATSHRMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117487215-B | Preparation method of double Beta-diketone-base colorless transparent polyimide film | 住井科技(深圳)有限公司 | 2024-11-05 | — | — | CN | claimed |
| CN-115181088-B | 2, 5-diacetylthiophene derivative and high-selectivity synthesis method thereof | 湖南大学 | 2024-03-29 | — | — | CN | claimed |
| CN-117487215-A | Preparation method of double Beta-diketone-base colorless transparent polyimide film | 住井科技(深圳)有限公司 | 2024-02-02 | — | — | CN | claimed |
| CN-114085218-B | Coumarin two-photon initiator and synthesis method and application thereof | 浙江大学 | 2023-09-08 | — | — | CN | claimed |
| CN-115181088-A | 2, 5-diacetylthiophene derivative and high-selectivity synthesis method thereof | 湖南大学 | 2022-10-14 | — | — | CN | claimed |
| EP-1753861-A2 | FRUCTOSEAMINE 3 KINASE AND THE FORMATION OF COLLAGEN AND ELASTIN | Dynamis Therapeutics, Inc. (US) | 2007-02-21 | — | — | EP | claimed |
| WO-2005079463-A2 | FRUCTOSEAMINE 3 KINASE AND THE FORMATION OF COLLAGEN AND ELASTIN | DYNAMIS THERAPEUTICS, INC. (US) | 2005-09-01 | — | — | WO | claimed |
| US-5101049-A | Novel thiophene derivatives and methods for producing the same | SEITETSU KAGAKU CO., LTD. (JP) | 1992-03-31 | — | — | US | claimed |
| JP-63246371-A | — | — | None | — | — | JP | disclosed |
| CN-119823106-A | Enhanced nucleic acid polymerization by aromatic compounds | 豪夫迈·罗氏有限公司 | 2025-04-15 | — | — | CN | disclosed |
| CN-114144520-B | Enhanced nucleic acid polymerization by aromatic compounds | 豪夫迈·罗氏有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-117487215-B | Preparation method of double Beta-diketone-base colorless transparent polyimide film | 住井科技(深圳)有限公司 | 2024-11-05 | — | — | CN | disclosed |
| CN-115181088-B | 2, 5-diacetylthiophene derivative and high-selectivity synthesis method thereof | 湖南大学 | 2024-03-29 | — | — | CN | disclosed |
| CN-115181088-B | 2, 5-diacetylthiophene derivative and high-selectivity synthesis method thereof | 湖南大学 | 2024-03-29 | — | — | CN | disclosed |
| US-4792612-A | MEDICINE INTERMEDIATES | SEITETSU KAGAKU CO., LTD. (JP) | 1988-12-20 | — | — | US | disclosed |
| JP-S63246371-A | TIOPHENE DERIVATIVE AND PRODUCTION THEREOF | SEITETSU KAGAKU CO LTD | 1988-10-13 | — | — | JP | disclosed |
| EP-0245835-A2 | Novel thiophene derivatives and methods for producing the same | SEITETSU KAGAKU CO., LTD. (JP) | 1987-11-19 | — | — | EP | disclosed |
| EP-0245835-A2 | Novel thiophene derivatives and methods for producing the same | SEITETSU KAGAKU CO., LTD. (JP) | 1987-11-19 | — | — | EP | disclosed |
| US-4153610-A | Process for producing 5-carboxy-2-acetylthiophene | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1979-05-08 | — | — | US | disclosed |
| US-4130566-A | Process for producing 5-carboxy-2-acetylthiophene | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1978-12-19 | — | — | US | disclosed |