Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 3/20 | 0.63 |
| ▸ | COMT | P21964 | 2/20 | 0.49 |
| ▸ | TPMT | P51580 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.37 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KRAS | P01116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28720678 | 1.00 | FTO (0.63) | FTOCOMTTPMTMEN1KMT2A | |
| SCHEMBL28717364 | 0.92 | FTO (0.61) | FTOCOMTTPMTMEN1KMT2A | |
| SCHEMBL28717367 | 0.92 | FTO (0.61) | FTOCOMTTPMTMEN1KMT2A | |
| SCHEMBL28717446 | 0.90 | FTO (0.51) | FTOCOMTTPMTMEN1KMT2A | |
| SCHEMBL28717457 | 0.90 | FTO (0.51) | FTOCOMTTPMTMEN1KMT2A | |
| SCHEMBL28717460 | 0.90 | FTO (0.51) | FTOCOMTTPMTMEN1KMT2A | |
| SCHEMBL28717443 | 0.90 | FTO (0.51) | FTOCOMTTPMTMEN1KMT2A | |
| SCHEMBL20100859 | 0.86 | FTO (0.83) | FTOCOMTTPMTMEN1KMT2A | |
| SCHEMBL29493665 | 0.86 | FTO (0.83) | FTOCOMTTPMTMEN1KMT2A | |
| SCHEMBL28717463 | 0.86 | FTO (0.83) | FTOCOMTTPMTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922316-B | FTO inhibitors | 北京生命科学研究所 | 2022-04-08 | — | — | CN | disclosed |