Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | HPGD | P15428 | 7/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28722650 | 0.97 | MAOB (0.71) | MAOBALDH1A1HPGDUSP2SMN1; SMN2 | |
| SCHEMBL12722470 | 0.93 | MAOB (0.71) | MAOBALDH1A1HPGDUSP2SMN1; SMN2 | |
| SCHEMBL21629528 | 0.88 | ALDH1A1 (0.81) | MAOBALDH1A1HPGDUSP2SMN1; SMN2 | |
| SCHEMBL28287385 | 0.88 | HPGD (0.57) | MAOBALDH1A1HPGDUSP2SMN1; SMN2 | |
| SCHEMBL12886696 | 0.87 | ALDH1A1 (0.77) | MAOBALDH1A1HPGDUSP2SMN1; SMN2 | |
| SCHEMBL12722471 | 0.85 | MAOB (0.71) | MAOBALDH1A1HPGDUSP2SMN1; SMN2 | |
| SCHEMBL12722468 | 0.85 | MAOB (0.71) | MAOBALDH1A1HPGDUSP2SMN1; SMN2 | |
| SCHEMBL21629627 | 0.84 | ALDH1A1 (0.83) | MAOBALDH1A1HPGDUSP2SMN1; SMN2 | |
| SCHEMBL8834992 | 0.82 | MAOB (0.67) | MAOBALDH1A1HPGDUSP2SMN1; SMN2 | |
| SCHEMBL24227373 | 0.81 | MAOB (0.65) | MAOBALDH1A1HPGDUSP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114349729-B | Coumarin derivative and preparation method and application thereof | 包头稀土研究院 | 2023-07-18 | — | — | CN | disclosed |
| CN-114349729-A | Coumarin derivative and preparation method and application thereof | 包头稀土研究院 | 2022-04-15 | — | — | CN | disclosed |