Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | KDM6B | O15054 | 1/20 | 0.47 |
| ▸ | TET3 | O43151 | 1/20 | 0.47 |
| ▸ | KDM4A | O75164 | 1/20 | 0.47 |
| ▸ | KDM4B | O94953 | 1/20 | 0.47 |
| ▸ | KDM5A | P29375 | 1/20 | 0.47 |
| ▸ | KDM5C | P41229 | 1/20 | 0.47 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.47 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.47 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28720778 | 1.00 | MAOA (0.54) | MAOAMAOBCYP19A1ALDH1A1CYP1A2 | |
| SCHEMBL28362719 | 0.95 | MAOA (0.58) | MAOAMAOBCYP19A1ALDH1A1CYP1A2 | |
| SCHEMBL28362720 | 0.95 | MAOA (0.58) | MAOAMAOBCYP19A1ALDH1A1CYP1A2 | |
| SCHEMBL28362765 | 0.91 | MAOA (0.52) | MAOAMAOBALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL28362767 | 0.91 | MAOA (0.52) | MAOAMAOBALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL28720593 | 0.87 | MAOA (0.61) | MAOAMAOBALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL28720595 | 0.87 | MAOA (0.61) | MAOAMAOBALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL28362570 | 0.86 | MAOA (0.54) | MAOAMAOBALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL28362566 | 0.86 | MAOA (0.54) | MAOAMAOBALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL28723609 | 0.85 | MAOA (0.63) | MAOAMAOBALDH1A1EGFRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110713487-B | Novel heterocyclic aromatic hydrazone derivative, pharmaceutically acceptable salt thereof, preparation method and application thereof | 南京大学 | 2022-02-15 | — | — | CN | disclosed |