Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.53 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | DGKA | P23743 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1332610 | 1.00 | NAAA (0.53) | NAAARAD52NPSR1FAAHDGKA | |
| SCHEMBL10825429 | 1.00 | NAAA (0.53) | NAAARAD52NPSR1FAAHDGKA | |
| SCHEMBL8147280 | 1.00 | NAAA (0.53) | NAAARAD52NPSR1FAAHDGKA | |
| SCHEMBL1072225 | 0.98 | NAAA (0.55) | NAAARAD52NPSR1FAAHDGKA | |
| SCHEMBL3257866 | 0.98 | NAAA (0.50) | NAAARAD52NPSR1FAAHDGKA | |
| SCHEMBL820029 | 0.98 | NAAA (0.55) | NAAARAD52NPSR1FAAHDGKA | |
| SCHEMBL5166272 | 0.98 | NAAA (0.55) | NAAARAD52NPSR1FAAHDGKA | |
| SCHEMBL2834493 | 0.95 | NAAA (0.44) | NAAARAD52NPSR1FAAHDGKA | |
| SCHEMBL9195940 | 0.90 | NAAA (0.50) | NAAARAD52NPSR1FAAHDGKA | |
| SCHEMBL676112 | 0.90 | NAAA (0.50) | NAAARAD52NPSR1FAAHDGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689051-B | Use of inhibitors of mitochondrial activity for the treatment of acute myeloid leukemia with poor prognosis | 蒙特利尔大学 | 2022-03-29 | — | — | CN | disclosed |