Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL634310 | 0.98 | ALDH1A1 (0.47) | ALDH1A1CYP3A4IDO1EP300KAT8 | |
| SCHEMBL1429875 | 0.80 | IDO1 (0.48) | ALDH1A1CYP3A4IDO1EP300KAT8 | |
| SCHEMBL17276025 | 0.78 | IDO1 (0.47) | ALDH1A1CYP3A4IDO1EP300KAT8 | |
| SCHEMBL2123973 | 0.78 | ALDH1A1 (0.52) | ALDH1A1CYP3A4IDO1EP300KAT8 | |
| SCHEMBL1429267 | 0.77 | IDO1 (0.45) | ALDH1A1CYP3A4IDO1EP300KAT8 | |
| SCHEMBL29689187 | 0.77 | IDO1 (0.45) | ALDH1A1CYP3A4IDO1EP300KAT8 | |
| SCHEMBL34472182 | 0.76 | KDM4E (0.33) | ALDH1A1CYP3A4TSHRHSD17B10HTT | |
| SCHEMBL8240850 | 0.76 | TUBB1 (0.43) | ALDH1A1CYP3A4LMNAHTTMAPT | |
| SCHEMBL16807230 | 0.76 | ALDH1A1 (0.56) | ALDH1A1CYP3A4IDO1EP300KAT8 | |
| SCHEMBL9847952 | 0.76 | TUBB1 (0.43) | ALDH1A1CYP3A4TSHRHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231614-A2 | QUINOLINE DERIVATIVES AND THEIR USE AS FUNGICIDES | Syngenta Participations AG (CH) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009087098-A2 | QUINOLINE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-07-16 | — | — | WO | disclosed |