SCHEMBL28723085

SCHEMBL28723085

C[C@@H](O)C1CCC(N)CC1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.33
SMYD3 Q9H7B4 1/20 0.32
DPP4 P27487 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14336109 1.00 ALOX5 (0.33) ALOX5SMYD3DPP4
SCHEMBL8227849 1.00 ALOX5 (0.33) ALOX5SMYD3DPP4
SCHEMBL4938530 1.00 ALOX5 (0.33) ALOX5SMYD3DPP4
SCHEMBL13775302 1.00 ALOX5 (0.33) ALOX5SMYD3DPP4
SCHEMBL18987904 1.00 ALOX5 (0.33) ALOX5SMYD3DPP4
Hydrochloric Acid SCHEMBL18988009 0.97 ALOX5 (0.32) ALOX5SMYD3DPP4
Hydrochloric Acid SCHEMBL18988007 0.97 ALOX5 (0.32) ALOX5SMYD3DPP4
Hydrochloric Acid SCHEMBL4933747 0.97 ALOX5 (0.32) ALOX5SMYD3DPP4
Hydrochloric Acid SCHEMBL21222289 0.97 ALOX5 (0.32) ALOX5SMYD3DPP4
Hydrochloric Acid SCHEMBL4933740 0.97 ALOX5 (0.32) ALOX5SMYD3DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119431323-A Heterobicyclic amides as CD38 inhibitors 贝林格尔·英格海姆国际有限公司 2025-02-14 CN disclosed
CN-114423753-B Heterobicyclic amides as CD38 inhibitors 里邦医疗公司 2024-09-17 CN disclosed
EP-4003980-A1 HETEROBICYCLIC AMIDES AS INHIBITORS OF CD38 Ribon Therapeutics Inc. (US) 2022-06-01 EP disclosed
CN-114423753-A Heterobicyclic amides as CD38 inhibitors 里邦医疗公司 2022-04-29 CN disclosed