Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EYA2 | O00167 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28724691 | 0.89 | TDP1 (0.37) | EYA2APPACETDP1ITGB3 | |
| Trifluoroacetic Acid SCHEMBL28724718 | 0.87 | HDAC1 (0.36) | ITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL28724723 | 0.83 | PIK3CD (0.42) | TDP1ITGB3ITGA2B | |
| SCHEMBL28724719 | 0.76 | TDP1 (0.32) | TDP1 | |
| SCHEMBL28724725 | 0.75 | HDAC1 (0.40) | EYA2APPACETDP1 | |
| SCHEMBL12226510 | 0.74 | PIK3CD (0.31) | — | |
| SCHEMBL30882137 | 0.72 | DDB1 (0.40) | — | |
| SCHEMBL1513993 | 0.71 | — | — | |
| Trifluoroacetic Acid SCHEMBL18953992 | 0.71 | TDP1 (0.36) | EYA2APPACETDP1 | |
| SCHEMBL13209127 | 0.71 | PIK3CD (0.50) | EYA2APPACETDP1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114349748-A | Indazole derivative, preparation method and medical application thereof | 四川海思科制药有限公司 | 2022-04-15 | — | — | CN | disclosed |