Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.30 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL28724723 | 0.91 | PIK3CD (0.42) | TRPV1PIK3CDNPC1RAB9AKDM4E | |
| SCHEMBL28724725 | 0.91 | HDAC1 (0.40) | HDAC1PIK3CDMEN1NPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL28724720 | 0.87 | EYA2 (0.30) | ITGB3ITGA2B | |
| SCHEMBL13209127 | 0.80 | PIK3CD (0.50) | PIK3CDNPC1RAB9AKDM4EPOLB | |
| SCHEMBL28724716 | 0.78 | TRPV1 (0.33) | HDAC1TRPV1PIK3CDMEN1NPC1 | |
| SCHEMBL12226514 | 0.77 | PIK3CD (0.41) | HDAC1TRPV1PIK3CDMEN1NPC1 | |
| SCHEMBL12226512 | 0.77 | PIK3CD (0.41) | HDAC1TRPV1PIK3CDMEN1NPC1 | |
| SCHEMBL28724691 | 0.76 | TDP1 (0.37) | KDM4ELMNAITGB3ITGA2B | |
| SCHEMBL28724715 | 0.73 | PIK3CD (0.33) | HDAC1PIK3CDMEN1NPC1RAB9A | |
| SCHEMBL3436810 | 0.72 | PIK3CD (0.40) | TRPV1PIK3CDMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114349748-A | Indazole derivative, preparation method and medical application thereof | 四川海思科制药有限公司 | 2022-04-15 | — | — | CN | disclosed |