SCHEMBL28728080

SCHEMBL28728080

CCCCNC(=S)Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1

nearest known ligand 0.74

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.74
SMN1; SMN2 Q16637 6/20 0.74
MEN1 O00255 6/20 0.74
LMNA P02545 5/20 0.74
HTT P42858 4/20 0.74
MYC P01106 1/20 0.56
MAX P61244 1/20 0.56
MAPT P10636 6/20 0.50
HPGD P15428 3/20 0.50
GAA P10253 2/20 0.50
CDK1 P06493 1/20 0.50
ALDH1A1 P00352 2/20 0.48
NPSR1 Q6W5P4 1/20 0.48
KDM4E B2RXH2 2/20 0.47
RECQL P46063 1/20 0.46
PABPC1 P11940 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18786284 0.91 MYC (0.61) KMT2ASMN1; SMN2MEN1LMNAHTT
SCHEMBL22469961 0.86 HPGD (0.60) KMT2ASMN1; SMN2MEN1LMNAHTT
SCHEMBL16323471 0.86 LMNA (0.85) KMT2ASMN1; SMN2MEN1LMNAHTT
SCHEMBL31276330 0.85 CDK1 (0.57) KMT2ASMN1; SMN2MEN1LMNAHTT
SCHEMBL2161427 0.84 MYC (0.61) KMT2ASMN1; SMN2MEN1LMNAHTT
SCHEMBL18776209 0.84 HPGD (0.61) KMT2ASMN1; SMN2MEN1LMNAHTT
SCHEMBL17596506 0.83 CDK1 (0.71) KMT2ASMN1; SMN2MEN1LMNAHTT
SCHEMBL23481254 0.81 MEN1 (0.50) KMT2ASMN1; SMN2MEN1LMNAHTT
SCHEMBL10053810 0.81 LMNA (0.55) KMT2ASMN1; SMN2MEN1LMNAHTT
SCHEMBL30413682 0.81 MYC (0.55) KMT2ASMN1; SMN2MEN1LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113999606-B Polyurethane waterproof coating and preparation method thereof 科顺防水科技股份有限公司 2022-04-01 CN claimed
CN-113999606-A Polyurethane waterproof coating and preparation method thereof 科顺防水科技股份有限公司 2022-02-01 CN claimed
CN-113999606-B Polyurethane waterproof coating and preparation method thereof 科顺防水科技股份有限公司 2022-04-01 CN disclosed
CN-113999606-A Polyurethane waterproof coating and preparation method thereof 科顺防水科技股份有限公司 2022-02-01 CN disclosed