Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28729204 | 0.92 | TDP1 (0.48) | TDP1PPARAHDAC1HDAC2NPC1 | |
| SCHEMBL13159243 | 0.83 | POLB (0.48) | TDP1HDAC1HDAC2NPC1GAA | |
| SCHEMBL1171609 | 0.83 | NR4A2 (0.49) | — | |
| SCHEMBL9375026 | 0.82 | TDP1 (0.55) | TDP1PPARANPC1GAAMAPT | |
| SCHEMBL3489319 | 0.81 | TAAR1 (0.51) | PPARAHDAC1HDAC2MAPTSMN1; SMN2 | |
| SCHEMBL7368880 | 0.80 | TDP1 (0.55) | TDP1PPARANPC1GAAMAPT | |
| SCHEMBL11656460 | 0.79 | TDP1 (0.55) | TDP1PPARAHDAC1HDAC2NPC1 | |
| SCHEMBL20654839 | 0.79 | TAAR1 (0.50) | PPARAMAPTSMN1; SMN2RECQLPOLB | |
| SCHEMBL8817229 | 0.78 | FAAH (0.50) | PPARAMAPTRECQLPOLBNPSR1 | |
| SCHEMBL8816751 | 0.78 | FAAH (0.50) | PPARAMAPTRECQLPOLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478609-B | Method for using thiophenol photocatalyst in defluorination alkylation or defluorination protonation reaction | 中国科学技术大学 | 2023-06-16 | — | — | CN | disclosed |
| CN-114478609-A | Method for applying thiophenol photocatalyst to defluorination alkylation or defluorination protonation reaction | 中国科学技术大学 | 2022-05-13 | — | — | CN | disclosed |