Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAK4 | O96013 | 2/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | DYRK2 | Q92630 | 5/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18317509 | 0.89 | PAK4 (0.44) | PAK4GABRA5HPGDHRH3STAT3 | |
| SCHEMBL18325813 | 0.82 | PAK4 (0.54) | PAK4GABRA5HPGDHRH3DYRK2 | |
| SCHEMBL29999255 | 0.82 | PAK4 (0.54) | PAK4GABRA5HPGDHRH3DYRK2 | |
| SCHEMBL29611902 | 0.82 | PAK4 (0.54) | PAK4GABRA5HPGDHRH3DYRK2 | |
| SCHEMBL18317788 | 0.80 | GABRA5 (0.43) | PAK4GABRA5HPGDHRH3STAT3 | |
| SCHEMBL18317597 | 0.80 | PAK4 (0.42) | PAK4GABRA5HPGDHRH3STAT3 | |
| SCHEMBL16345168 | 0.80 | PAK4 (0.43) | PAK4GABRA5HPGDHRH3STAT3 | |
| SCHEMBL18317547 | 0.80 | GABRA5 (0.41) | PAK4GABRA5HRH3STAT3LRRK2 | |
| SCHEMBL24145505 | 0.78 | PAK4 (0.45) | PAK4GABRA5HPGDHRH3STAT3 | |
| SCHEMBL16347314 | 0.78 | GABRA5 (0.41) | PAK4GABRA5HPGDHRH3STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440515-B | Substituted benzofuranyl and benzoxazolyl compounds and uses thereof | 卡尔约药物治疗公司 | 2022-05-03 | — | — | CN | disclosed |