SCHEMBL28730199

SCHEMBL28730199

CNc1nc2cc(Br)cc(Cl)c2o1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.35
FBP1 P09467 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14758466 0.77 MAPT (0.33) ELANE
SCHEMBL22561676 0.77 NMT1 (0.31)
SCHEMBL16379763 0.76 PDE7B (0.44)
SCHEMBL22561707 0.75 PIK3CA (0.34) ELANE
SCHEMBL19922859 0.74 NUDT1 (0.44) ELANE
SCHEMBL18325751 0.73 PDE7B (0.41)
SCHEMBL25057060 0.72 ELANE (0.51) ELANE
SCHEMBL22660185 0.71 ELANE (0.36) ELANE
SCHEMBL18317507 0.71 NOTUM (0.32)
SCHEMBL29611877 0.71 NOTUM (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108440515-B Substituted benzofuranyl and benzoxazolyl compounds and uses thereof 卡尔约药物治疗公司 2022-05-03 CN disclosed