Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.59 |
| ▸ | FPR3 | P25089 | 1/20 | 0.53 |
| ▸ | FPR2 | P25090 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8258345 | 0.89 | NAMPT (0.59) | NAMPTFPR3FPR2MAPTTDP1 | |
| SCHEMBL4922883 | 0.86 | NAMPT (0.63) | NAMPTMAPTHDAC1NPC1SMN1; SMN2 | |
| SCHEMBL19694494 | 0.85 | NAMPT (0.62) | NAMPTFPR3FPR2MAPTTDP1 | |
| SCHEMBL26130392 | 0.85 | POLB (0.57) | NAMPTFPR3FPR2MAPTTDP1 | |
| SCHEMBL3180689 | 0.84 | L3MBTL1 (0.61) | NAMPTFPR3FPR2MAPTTDP1 | |
| SCHEMBL16193025 | 0.84 | NAMPT (0.60) | NAMPTFPR3FPR2MAPTTDP1 | |
| SCHEMBL2589540 | 0.84 | NAMPT (0.60) | NAMPTFPR3FPR2MAPTTDP1 | |
| SCHEMBL8253777 | 0.84 | NAMPT (0.60) | NAMPTFPR3FPR2MAPTTDP1 | |
| SCHEMBL15344407 | 0.84 | NAMPT (0.60) | NAMPTHDAC1HDAC6NPC1L3MBTL1 | |
| SCHEMBL23899245 | 0.83 | NAMPT (0.72) | NAMPTFPR3FPR2MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109612981-B | Recognition of cellular target binding of bioactive agents using intracellular bioluminescence resonance energy transfer | 普洛麦格公司 | 2022-05-13 | — | — | CN | disclosed |