Iodide

Iodide

SCHEMBL2873145

CCCCCCCCCCCCC(O)COc1ccc(Br)c(-c2ccccc2)c1.I

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 2/20 0.42
PLA2G4B P0C869 2/20 0.42
MAPT P10636 2/20 0.41
S1PR1 P21453 1/20 0.41
PTPN1 P18031 1/20 0.41
HTT P42858 1/20 0.41
MAPK1 P28482 2/20 0.40
KDM4E B2RXH2 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
ALDH1A1 P00352 1/20 0.38
GAA P10253 1/20 0.38
PTPN11 Q06124 3/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
SOAT1 P35610 1/20 0.37
POLB P06746 1/20 0.37
SLC2A1 P11166 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL2875873 0.86 PRMT5 (0.44) HDAC8PLA2G4BMAPTS1PR1PTPN1
SCHEMBL15103815 0.86 PLA2G4B (0.43) HDAC8PLA2G4BMAPTS1PR1PTPN1
Hydrochloric Acid SCHEMBL1043604 0.85 PLA2G4B (0.43) HDAC8PLA2G4BMAPTS1PR1PTPN1
Hydrochloric Acid SCHEMBL1150005 0.85 PLA2G4B (0.43) HDAC8PLA2G4BMAPTS1PR1PTPN1
Bromide SCHEMBL1149921 0.85 PLA2G4B (0.43) HDAC8PLA2G4BMAPTS1PR1PTPN1
Bromide SCHEMBL1046059 0.85 PLA2G4B (0.43) HDAC8PLA2G4BMAPTS1PR1PTPN1
SCHEMBL21990 0.78 PLA2G4B (0.55) PLA2G4BMAPTS1PR1HTTKDM4E
SCHEMBL9797915 0.78 PLA2G4B (0.55) PLA2G4BMAPTS1PR1HTTKDM4E
SCHEMBL9797717 0.78 PLA2G4B (0.55) PLA2G4BMAPTS1PR1HTTKDM4E
SCHEMBL6231558 0.78 PLA2G4B (0.55) PLA2G4BMAPTS1PR1HTTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2461397-A1 ELECTRODE ACTIVE MATERIAL, ELECTRODE, AND ELECTRICITY STORAGE DEVICE Dow Corning Toray Co., Ltd. (JP) 2012-06-06 EP disclosed
EP-2241586-A1 SILICON-CONTAINING PARTICLE, PROCESS FOR PRODUCING THE SAME, ORGANIC-POLYMER COMPOSITION, CERAMIC, AND PROCESS FOR PRODUCING THE SAME Dow Corning Toray Co., Ltd. (JP) 2010-10-20 EP disclosed