Iodide

Iodide

SCHEMBL2875873

CCCCCCCCCCCCC(O)COc1ccc(Cl)c(-c2ccccc2)c1.I

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PRMT5 O14744 3/20 0.44
WDR77 Q9BQA1 3/20 0.44
FFAR4 Q5NUL3 2/20 0.44
FFAR1 O14842 1/20 0.44
PLA2G4B P0C869 2/20 0.42
KMT2A Q03164 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HTT P42858 2/20 0.41
S1PR1 P21453 1/20 0.41
MAPT P10636 1/20 0.41
HDAC8 Q9BY41 2/20 0.40
PTPN1 P18031 1/20 0.38
HTR1A P08908 1/20 0.38
HTR7 P34969 1/20 0.38
PTPN11 Q06124 2/20 0.38
MEN1 O00255 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL2873145 0.86 HDAC8 (0.42) PLA2G4BKMT2AHTTS1PR1MAPT
SCHEMBL15103815 0.86 PLA2G4B (0.43) PLA2G4BHTTS1PR1MAPTHDAC8
Hydrochloric Acid SCHEMBL1043604 0.85 PLA2G4B (0.43) PLA2G4BHTTS1PR1MAPTHDAC8
Bromide SCHEMBL1046059 0.85 PLA2G4B (0.43) PLA2G4BHTTS1PR1MAPTHDAC8
Bromide SCHEMBL1149921 0.85 PLA2G4B (0.43) PLA2G4BHTTS1PR1MAPTHDAC8
Hydrochloric Acid SCHEMBL1150005 0.85 PLA2G4B (0.43) PLA2G4BHTTS1PR1MAPTHDAC8
SCHEMBL21990 0.78 PLA2G4B (0.55) PLA2G4BKMT2AHTTS1PR1MAPT
SCHEMBL6231558 0.78 PLA2G4B (0.55) PLA2G4BKMT2AHTTS1PR1MAPT
SCHEMBL382120 0.78 PLA2G4B (0.55) PLA2G4BKMT2AHTTS1PR1MAPT
SCHEMBL9797915 0.78 PLA2G4B (0.55) PLA2G4BKMT2AHTTS1PR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2461397-A1 ELECTRODE ACTIVE MATERIAL, ELECTRODE, AND ELECTRICITY STORAGE DEVICE Dow Corning Toray Co., Ltd. (JP) 2012-06-06 EP disclosed
EP-2241586-A1 SILICON-CONTAINING PARTICLE, PROCESS FOR PRODUCING THE SAME, ORGANIC-POLYMER COMPOSITION, CERAMIC, AND PROCESS FOR PRODUCING THE SAME Dow Corning Toray Co., Ltd. (JP) 2010-10-20 EP disclosed