Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | NMT1 | P30419 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25668716 | 0.84 | MAPT (0.63) | MAPTTDP1POLBNPC1RAB9A | |
| SCHEMBL20150737 | 0.82 | MAPT (0.67) | MAPTTDP1POLBNPC1RAB9A | |
| SCHEMBL28733084 | 0.82 | MEN1 (0.56) | MAPTPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL6996164 | 0.81 | MAPT (0.70) | MAPTTDP1POLBNPC1RAB9A | |
| SCHEMBL28975445 | 0.81 | MAPT (0.59) | MAPTTDP1POLBNPC1RAB9A | |
| SCHEMBL28939191 | 0.81 | NPC1 (0.52) | MAPTPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL9676988 | 0.80 | POLB (0.57) | MAPTPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL12618875 | 0.79 | MAPT (0.58) | MAPTTDP1POLBNPC1RAB9A | |
| SCHEMBL28733079 | 0.79 | HSD17B10 (0.59) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL12755626 | 0.78 | MAPT (0.56) | MAPTTDP1POLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114436882-B | Synthesis method of asymmetric oxamide derivative | 浙江工业大学 | 2023-09-19 | — | — | CN | disclosed |
| CN-114436882-A | Method for synthesizing asymmetric oxamide derivative | 浙江工业大学 | 2022-05-06 | — | — | CN | disclosed |