Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25668716 | 0.84 | MAPT (0.63) | MAPTTDP1POLBNPC1RAB9A | |
| SCHEMBL28733085 | 0.81 | MAPT (0.59) | MAPTTDP1POLBNPC1RAB9A | |
| SCHEMBL5067395 | 0.81 | MAPT (0.42) | MAPTPOLBRAB9AALDH1A1KMT2A | |
| SCHEMBL28975452 | 0.81 | NPC1 (0.52) | MAPTNPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL28975454 | 0.80 | HTT (0.59) | NPC1RAB9AALDH1A1KMT2ALMNA | |
| SCHEMBL29077383 | 0.80 | POLB (0.57) | MAPTPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL28975443 | 0.79 | HSD17B10 (0.59) | NPC1RAB9AALDH1A1KMT2AKDM4E | |
| SCHEMBL178429 | 0.78 | MAPT (0.71) | MAPTTDP1POLBNPC1RAB9A | |
| SCHEMBL30729658 | 0.76 | MAPT (0.69) | MAPTTDP1POLBNPC1RAB9A | |
| SCHEMBL11139077 | 0.76 | MAPT (0.63) | MAPTTDP1POLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115322131-B | Synthesis method of beta-fluoroindole acrylamide compound | 温州大学 | 2023-08-22 | — | — | CN | disclosed |
| CN-113402412-B | (E) Method for synthesizing (E) -beta-fluoroacrylamide derivative | 温州大学 | 2023-02-14 | — | — | CN | disclosed |