⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL478011 | 0.97 | — | — | |
| SCHEMBL17556551 | 0.97 | — | — | |
| SCHEMBL828360 | 0.90 | — | — | |
| SCHEMBL28477048 | 0.71 | — | — | |
| SCHEMBL2285871 | 0.71 | — | — | |
| SCHEMBL18410114 | 0.69 | — | — | |
| SCHEMBL28476388 | 0.69 | — | — | |
| SCHEMBL19006856 | 0.69 | — | — | |
| SCHEMBL478015 | 0.68 | — | — | |
| SCHEMBL960841 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770214-B | Heterocyclic P2X7 antagonists | 布雷耶疗法有限公司 | 2024-03-29 | — | — | CN | claimed |
| US-11623919-B2 | Heterocyclic P2X7 antagonists | BREYE THERAPEUTICS APS (DK) | 2023-04-11 | — | — | US | claimed |
| CN-115315421-A | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2022-11-08 | — | — | CN | claimed |
| CN-115298177-A | Bicyclic amines as CDK2 inhibitors | 因赛特公司 | 2022-11-04 | — | — | CN | claimed |
| CN-111201226-B | Cyclic substituted imidazo [4,5-c ] quinoline derivatives | 辉瑞大药厂 | 2022-07-22 | — | — | CN | claimed |
| EP-3592740-B1 | CYCLIC SUBSTITUTED IMIDAZO[4,5-C]QUINOLINE DERIVATIVES | PFIZER (US) | 2022-02-09 | — | — | EP | claimed |
| US-11161844-B2 | Cyclic substituted imidazo[4,5-c]quinoline derivatives | PFIZER INC. (US) | 2021-11-02 | — | — | US | claimed |
| WO-2021117846-A1 | COMPOUND SERVING AS PDGF RECEPTOR KINASE INHIBITOR, AND COMPOSITION | 日本新薬株式会社 | 2021-06-17 | — | — | WO | claimed |
| CN-111201226-A | Cyclic substituted imidazo [4,5-c ] quinoline derivatives | 辉瑞大药厂 | 2020-05-26 | — | — | CN | claimed |
| EP-3619200-A1 | HETEROCYCLIC P2X7 ANTAGONISTS | AXXAM S.p.A. (IT) | 2020-03-11 | — | — | EP | claimed |
| US-20200055831-A1 | HETEROCYCLIC P2X7 ANTAGONISTS | BREYE THERAPEUTICS APS (DK) | 2020-02-20 | — | — | US | claimed |
| CN-110770214-A | Heterocyclic P2X7 antagonists | 阿克萨姆股份公司 | 2020-02-07 | — | — | CN | claimed |
| US-20200039977-A1 | CYCLIC SUBSTITUTED IMIDAZO[4,5-C]QUINOLINE DERIVATIVES | PFIZER (US) | 2020-02-06 | — | — | US | claimed |
| WO-2018202694-A1 | HETEROCYCLIC P2X7 ANTAGONISTS | AXXAM S.P.A. (IT) | 2018-11-08 | — | — | WO | claimed |
| EP-3398941-A1 | HETEROCYCLIC P2X7 ANTAGONISTS | AXXAM S.p.A. (IT) | 2018-11-07 | — | — | EP | claimed |
| WO-2018163030-A1 | CYCLIC SUBSTITUTED IMIDAZO[4,5-C]QUINOLINE DERIVATIVES | PFIZER INC. (US) | 2018-09-13 | — | — | WO | claimed |
| WO-2014124988-A1 | PYRIDINE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA LIMITED (GB) | 2014-08-21 | — | — | WO | claimed |
| US-5948792-A | POTENT AND SELECTIVE ANTAGONISTS FOR MUSCARINIC M.SUB.3 RECEPTORS WITH LITTLE SIDE EFFECTS. | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-07 | — | — | US | claimed |
| CN-1226888-A | Fluorinated 1,4-disubstituted piperidine derivatives | BANYU PHARMA CO LTD (JP) | 1999-08-25 | — | — | CN | claimed |
| EP-0930298-A1 | FLUORINATED 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-07-21 | — | — | EP | claimed |