Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 13/20 | 0.52 |
| ▸ | NPC1 | O15118 | 11/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | CASP3 | P42574 | 2/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 2/20 | 0.47 |
| ▸ | SRC | P12931 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28734841 | 0.93 | RAB9A (0.57) | LMNARAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL28734870 | 0.93 | RAB9A (0.56) | LMNARAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL28734855 | 0.91 | ABL1 (0.52) | LMNARAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL28734869 | 0.88 | SMN1; SMN2 (0.57) | LMNARAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL28734860 | 0.83 | NPC1 (0.55) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL28734856 | 0.83 | ABL1 (0.65) | LMNARAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL28734874 | 0.81 | ABL1 (0.58) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL28734837 | 0.81 | MAPT (0.47) | LMNARAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL28734853 | 0.79 | ABL1 (0.65) | LMNARAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL14970871 | 0.78 | RAB9A (0.74) | LMNARAB9ANPC1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114195772-B | 1,2, 4-oxadiazole derivative containing 1,3, 4-thiadiazole unit, and preparation method and application thereof | 贵州大学 | 2023-06-30 | — | — | CN | claimed |
| CN-114195772-A | 1,2, 4-oxadiazole derivative containing 1,3, 4-thiadiazole unit and preparation method and application thereof | 贵州大学 | 2022-03-18 | — | — | CN | claimed |
| CN-114195772-B | 1,2, 4-oxadiazole derivative containing 1,3, 4-thiadiazole unit, and preparation method and application thereof | 贵州大学 | 2023-06-30 | — | — | CN | disclosed |
| CN-114195772-A | 1,2, 4-oxadiazole derivative containing 1,3, 4-thiadiazole unit and preparation method and application thereof | 贵州大学 | 2022-03-18 | — | — | CN | disclosed |