Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28939448 | 0.85 | KCNH2 (0.51) | KCNH2CACNA1IPOLBMCHR1MAPT | |
| SCHEMBL29658301 | 0.81 | SCN9A (0.56) | KCNH2CACNA1IPOLBLMNANPSR1 | |
| SCHEMBL28735380 | 0.81 | SCN9A (0.56) | KCNH2CACNA1IPOLBLMNANPSR1 | |
| SCHEMBL28735483 | 0.79 | KCNH2 (0.46) | KCNH2CACNA1IPOLBALDH1A1LMNA | |
| SCHEMBL28735428 | 0.78 | KCNH2 (0.48) | KCNH2CACNA1IPOLBLMNAMAPT | |
| SCHEMBL28735464 | 0.78 | KCNH2 (0.48) | KCNH2CACNA1IPOLBLMNAMAPT | |
| SCHEMBL16055793 | 0.78 | P2RX1 (0.47) | POLBALDH1A1P2RX1MAPTNPSR1 | |
| SCHEMBL28735419 | 0.78 | P2RX1 (0.46) | POLBALDH1A1LMNAHTTP2RX1 | |
| SCHEMBL29658348 | 0.78 | P2RX1 (0.46) | POLBALDH1A1LMNAHTTP2RX1 | |
| SCHEMBL31349323 | 0.76 | POLB (0.65) | POLBALDH1A1LMNAHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478366-A | Pyridone derivative and application thereof in medicine | 海思科医药集团股份有限公司 | 2022-05-13 | — | — | CN | disclosed |