Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29945589 | 0.97 | POLB (0.65) | POLBHTTLMNAALDH1A1ALOX5 | |
| SCHEMBL5118138 | 0.84 | POLB (0.61) | POLBHTTALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL29945642 | 0.84 | POLB (0.58) | POLBALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL28871798 | 0.84 | POLB (0.58) | POLBALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL1326710 | 0.80 | POLB (0.51) | POLBHTTLMNAALDH1A1ALOX5 | |
| Hydrochloric Acid SCHEMBL4032484 | 0.79 | POLB (0.76) | POLBLMNAALDH1A1L3MBTL1CYP3A4 | |
| Hydrochloric Acid SCHEMBL4032486 | 0.79 | POLB (0.76) | POLBLMNAALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL5946839 | 0.78 | POLB (0.72) | POLBHTTALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL29945641 | 0.78 | ALDH1A1 (0.58) | POLBLMNAALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL17434345 | 0.77 | ALDH1A1 (0.57) | POLBALDH1A1L3MBTL1CYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743446-A1 | NITRO-CONTAINING COMPOUNDS THAT KILL MYCOBACTERIA | Board of Trustees of Michigan State University (US) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025015066-A1 | NITRO-CONTAINING COMPOUNDS THAT KILL MYCOBACTERIA | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2025-01-16 | — | — | WO | disclosed |