Benzoquinone

Benzoquinone

SCHEMBL28737726

CC(C)(C)C1=CC(=Cc2ccccc2)C=C(C(C)(C)C)C1=O.O=C1C=CC(=O)C=C1

nearest known ligand 0.51

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 3/20 0.51
KMT2A Q03164 3/20 0.51
NPC1 O15118 1/20 0.51
GPR35 Q9HC97 1/20 0.51
POLB P06746 1/20 0.38
GPR55 Q9Y2T6 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
CYP1A2 P05177 4/20 0.37
F3 P13726 1/20 0.35
NFKB1 P19838 2/20 0.35
NFKB2 Q00653 2/20 0.35
RELA Q04206 2/20 0.35
MAPT P10636 5/20 0.33
NPSR1 Q6W5P4 3/20 0.33
HPGD P15428 3/20 0.33
ALDH1A1 P00352 3/20 0.33
CYP2C19 P33261 2/20 0.33
RAF1 P04049 1/20 0.33
CDK1 P06493 1/20 0.33
CYP2C9 P11712 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoquinone SCHEMBL23209758 0.98 KMT2A (0.50) ATMKMT2ANPC1GPR35POLB
SCHEMBL86407 0.93 ATM (0.56) ATMKMT2ANPC1GPR35POLB
Hno SCHEMBL6475533 0.90 ATM (0.54) ATMKMT2ANPC1GPR35POLB
SCHEMBL19730332 0.84 KMT2A (0.66) ATMKMT2ANPC1GPR35POLB
SCHEMBL38660251 0.84 ATM (0.55) ATMKMT2ANPC1GPR35POLB
SCHEMBL19730329 0.81 ATM (0.63) ATMKMT2ANPC1GPR35POLB
SCHEMBL7587342 0.79 NFKB1 (0.42) ATMKMT2ANPC1GPR35POLB
SCHEMBL7587340 0.79 NFKB1 (0.42) ATMKMT2ANPC1GPR35POLB
SCHEMBL2148644 0.78 ATM (0.59) ATMKMT2ANPC1GPR35POLB
SCHEMBL28498504 0.78 ATM (0.59) ATMKMT2ANPC1GPR35POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114502522-A Methylated quinone and ammonium salt anti-polymerization agent compositions and methods 埃科莱布美国股份有限公司 2022-05-13 CN disclosed