Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.71 |
| ▸ | ALB | P02768 | 1/20 | 0.71 |
| ▸ | MAOA | P21397 | 1/20 | 0.71 |
| ▸ | CNR1 | P21554 | 1/20 | 0.71 |
| ▸ | DRD1 | P21728 | 1/20 | 0.71 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.71 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.71 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29573898 | 1.00 | TTR (0.71) | TTRALBMAOACNR1DRD1 | |
| SCHEMBL23729866 | 0.84 | TTR (0.65) | TTRALBMAOACNR1DRD1 | |
| SCHEMBL16689757 | 0.84 | TTR (0.72) | TTRALBMAOACNR1DRD1 | |
| Tafamidis SCHEMBL442508 | 0.83 | TTR (1.00) | TTRALBMAOACNR1DRD1 | |
| Tafamidis SCHEMBL29361223 | 0.83 | TTR (1.00) | TTRALBMAOACNR1DRD1 | |
| SCHEMBL23729417 | 0.83 | TTR (0.57) | TTRALBMAOACNR1DRD1 | |
| SCHEMBL23729426 | 0.83 | TTR (0.57) | TTRALBMAOACNR1DRD1 | |
| SCHEMBL23729862 | 0.83 | TTR (0.57) | TTRALBMAOACNR1DRD1 | |
| SCHEMBL23729861 | 0.82 | TTR (0.54) | TTRALBMAOACNR1DRD1 | |
| SCHEMBL23729867 | 0.82 | TTR (0.63) | TTRALBMAOACNR1DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114369071-A | Synthetic method of tafamidis intermediate | 湖南第一师范学院 | 2022-04-19 | — | — | CN | disclosed |