Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.39 |
| ▸ | CFB | P00751 | 3/20 | 0.39 |
| ▸ | PRCP | P42785 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2873832 | 0.88 | SCN10A (0.40) | SCN10ATAAR1AAK1CFBPRCP | |
| SCHEMBL13119215 | 0.80 | KDM4E (0.53) | SCN10ACFBMAPK10PIN1KDM4E | |
| SCHEMBL2872947 | 0.79 | CSNK1D (0.41) | SCN10ATAAR1AAK1CFBKDM4E | |
| SCHEMBL6245308 | 0.74 | SCN10A (0.39) | SCN10ATAAR1AAK1CFBPRCP | |
| SCHEMBL15311202 | 0.73 | AAK1 (0.60) | SCN10ATAAR1AAK1 | |
| SCHEMBL2866759 | 0.73 | ALDH1A1 (0.39) | TAAR1AAK1PRCPKDM4ELMNA | |
| Trifluoroacetic Acid SCHEMBL5100346 | 0.72 | SCN10A (0.45) | SCN10ACFBPRCPMAPK10PIN1 | |
| SCHEMBL6241625 | 0.72 | PRCP (0.40) | SCN10ACFBPRCPMAPK10PIN1 | |
| SCHEMBL7653718 | 0.71 | TDP1 (0.47) | MAPK10PIN1 | |
| SCHEMBL24244074 | 0.71 | CFB (0.40) | SCN10ACFBPRCPMAPK10PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010103306-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS ANTIVARAL AGENTS | ASTRAZENECA UK LIMITED (GB) | 2010-09-16 | — | — | WO | disclosed |