Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 15/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 14/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 8/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7092189 | 0.76 | EPHX2 (0.44) | HDAC6 | |
| SCHEMBL22401242 | 0.70 | NNMT (0.42) | — | |
| SCHEMBL2813818 | 0.68 | HDAC1 (0.79) | HDAC1HDAC2ALOX5HDAC8HDAC6 | |
| SCHEMBL2810504 | 0.68 | HDAC1 (0.79) | HDAC1HDAC2ALOX5HDAC8HDAC6 | |
| SCHEMBL29055202 | 0.68 | HDAC1 (0.79) | HDAC1HDAC2ALOX5HDAC8HDAC6 | |
| Suberohydroxamic Acid SCHEMBL2159033 | 0.67 | HDAC1 (1.00) | HDAC1HDAC2ALOX5HDAC8HDAC6 | |
| SCHEMBL11769965 | 0.67 | HDAC1 (1.00) | HDAC1HDAC2ALOX5HDAC8HDAC6 | |
| SCHEMBL10439098 | 0.67 | HDAC1 (1.00) | HDAC1HDAC2ALOX5HDAC8HDAC6 | |
| Azelaic Bis Hydroxamic Acid SCHEMBL4741072 | 0.67 | HDAC1 (1.00) | HDAC1HDAC2ALOX5HDAC8HDAC6 | |
| SCHEMBL11767258 | 0.67 | HDAC1 (1.00) | HDAC1HDAC2ALOX5HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114380751-A | Indane amine derivatives, preparation method and application thereof | 上海辉启生物医药科技有限公司 | 2022-04-22 | — | — | CN | disclosed |