Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.63 |
| ▸ | ECE1 | P42892 | 2/20 | 0.63 |
| ▸ | CASP3 | P42574 | 2/20 | 0.62 |
| ▸ | CASP1 | P29466 | 1/20 | 0.62 |
| ▸ | CASP9 | P55211 | 1/20 | 0.62 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.61 |
| ▸ | ACE | P12821 | 1/20 | 0.58 |
| ▸ | CTSL | P07711 | 3/20 | 0.57 |
| ▸ | TACR1 | P25103 | 2/20 | 0.57 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.56 |
| ▸ | CTSB | P07858 | 1/20 | 0.56 |
| ▸ | CTSS | P25774 | 1/20 | 0.56 |
| ▸ | CTSK | P43235 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14778231 | 1.00 | MME (0.63) | MMEECE1CASP3CASP1CASP9 | |
| SCHEMBL14433746 | 0.96 | ECE1 (0.63) | MMEECE1CASP3CASP1CASP9 | |
| SCHEMBL13884433 | 0.96 | ECE1 (0.63) | MMEECE1CASP3CASP1CASP9 | |
| SCHEMBL6552944 | 0.96 | ECE1 (0.63) | MMEECE1CASP3CASP1CASP9 | |
| SCHEMBL13589992 | 0.96 | ECE1 (0.63) | MMEECE1CASP3CASP1CASP9 | |
| SCHEMBL6552949 | 0.96 | ECE1 (0.63) | MMEECE1CASP3CASP1CASP9 | |
| SCHEMBL10397579 | 0.95 | MME (0.67) | MMEECE1NAALAD2ACECTSL | |
| SCHEMBL13957718 | 0.91 | MME (0.64) | MMEECE1CASP3CASP1CASP9 | |
| SCHEMBL13884435 | 0.91 | MME (0.64) | MMEECE1CASP3CASP1CASP9 | |
| SCHEMBL1426719 | 0.91 | MME (0.64) | MMEECE1CASP3CASP1CASP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8729464-B2 | Method for determining stage of chronic kidney disease, device therefor and method for operating the same | Tanaka, Noriaki (JP) | 2014-05-20 | — | — | US | disclosed |
| EP-2579033-A1 | METHOD FOR DETERMINING STAGE OF CHRONIC KIDNEY DISEASE, DEVICE THEREFOR AND METHOD FOR OPERATING THE SAME | Tanaka, Noriaki (JP) | 2013-04-10 | — | — | EP | disclosed |
| US-20130068945-A1 | METHOD FOR DETERMINING STAGE OF CHRONIC KIDNEY DISEASE, DEVICE THEREFOR AND METHOD FOR OPERATING THE SAME | Tanaka, Noriaki (JP) | 2013-03-21 | — | — | US | disclosed |
| WO-2010126146-A1 | METHOD OR APPARATUS FOR DETERMINATION OF SEVERITY OF RENAL DISEASES AND METHOD FOR OPERATION OF THE APPARATUS | TANAKA NORIAKI (JP) | 2010-11-04 | — | — | WO | disclosed |