Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.64 |
| ▸ | ECE1 | P42892 | 3/20 | 0.64 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.62 |
| ▸ | CTSL | P07711 | 3/20 | 0.58 |
| ▸ | TACR1 | P25103 | 2/20 | 0.58 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.57 |
| ▸ | ACE | P12821 | 1/20 | 0.57 |
| ▸ | CTSB | P07858 | 1/20 | 0.57 |
| ▸ | CTSS | P25774 | 1/20 | 0.57 |
| ▸ | CTSK | P43235 | 1/20 | 0.57 |
| ▸ | CASP1 | P29466 | 2/20 | 0.56 |
| ▸ | CASP3 | P42574 | 2/20 | 0.56 |
| ▸ | CASP9 | P55211 | 2/20 | 0.56 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13884435 | 1.00 | MME (0.64) | MMEECE1NAALAD2CTSLTACR1 | |
| SCHEMBL13957718 | 1.00 | MME (0.64) | MMEECE1NAALAD2CTSLTACR1 | |
| SCHEMBL14433746 | 0.95 | ECE1 (0.63) | MMEECE1NAALAD2CTSLTACR1 | |
| SCHEMBL13884433 | 0.95 | ECE1 (0.63) | MMEECE1NAALAD2CTSLTACR1 | |
| SCHEMBL13589992 | 0.95 | ECE1 (0.63) | MMEECE1NAALAD2CTSLTACR1 | |
| SCHEMBL6552949 | 0.95 | ECE1 (0.63) | MMEECE1NAALAD2CTSLTACR1 | |
| SCHEMBL6552944 | 0.95 | ECE1 (0.63) | MMEECE1NAALAD2CTSLTACR1 | |
| SCHEMBL10397579 | 0.95 | MME (0.67) | MMEECE1NAALAD2CTSLTACR1 | |
| SCHEMBL9697579 | 0.94 | MME (0.65) | MMEECE1NAALAD2CTSLFOLH1 | |
| SCHEMBL14493648 | 0.93 | MME (0.58) | MMEECE1NAALAD2CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9688777-B2 | Protein-polymer complex, TGase substrate-containing polymer, TGase substrate-containing monomer, method for producing protein-polymer complex, and method for improving protein function at solid-liquid interface or in vicinity of solid-liquid interface | HITACHI, LTD. (JP) | 2017-06-27 | — | — | US | disclosed |
| US-20160251450-A1 | PROTEIN-POLYMER COMPLEX, TGase SUBSTRATE-CONTAINING POLYMER, TGase SUBSTRATE-CONTAINING MONOMER, METHOD FOR PRODUCING PROTEIN-POLYMER COMPLEX, AND METHOD FOR IMPROVING PROTEIN FUNCTION AT SOLID-LIQUID INTERFACE OR IN VICINITY OF SOLID-LIQUID INTERFACE | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2016-09-01 | — | — | US | disclosed |
| US-9388454-B2 | Method for producing protein-nucleic acid conjugate, and method for detecting target substance | KYUSHU UNIVERSITY, NAT'L UNIVERSITY CORPORATION (JP) | 2016-07-12 | — | — | US | disclosed |
| EP-3015474-A1 | PROTEIN-POLYMER COMPLEX, TGase SUBSTRATE-CONTAINING POLYMER, TGase SUBSTRATE-CONTAINING MONOMER, METHOD FOR PRODUCING PROTEIN-POLYMER COMPLEX, AND METHOD FOR IMPROVING PROTEIN FUNCTION ON INTERFACE OR IN VICINITIY OF INTERFACE OF SOLID-LIQUID | Kyushu University, National University Corporation (JP) | 2016-05-04 | — | — | EP | disclosed |
| EP-2301946-B1 | NUCLEOSIDE TRIPHOSPHATE DERIVATIVE, NUCLEIC ACID PROBE, MULTILABELED NUCLEIC ACID PROBE, METHOD FOR PRODUCTION OF MULTILABELED NUCLEIC ACID PROBE, AND METHOD FOR DETECTION OF TARGET NUCLEIC ACID | UNIV KYUSHU NAT UNIV CORP (JP) | 2016-01-06 | — | — | EP | disclosed |
| US-20150284762-A1 | METHOD FOR PRODUCING PROTEIN-NUCLEIC ACID CONJUGATE, AND METHOD FOR DETECTING TARGET SUBSTANCE | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2015-10-08 | — | — | US | disclosed |
| EP-2865762-A1 | METHOD FOR PRODUCING PROTEIN-NUCLEIC ACID COMPLEX, AND METHOD FOR DETECTING TARGET SUBSTANCE | Kyushu University, National University Corporation (JP) | 2015-04-29 | — | — | EP | disclosed |
| US-8198418-B2 | Nucleoside triphosphate derivative, nucleic acid probe, multilabeled nucleic acid probe, method for production of multilabeled nucleic acid probe, and method for detection of target nucleic acid | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2012-06-12 | — | — | US | disclosed |
| US-20110189671-A1 | NUCLEOSIDE TRIPHOSPHATE DERIVATIVE, NUCLEIC ACID PROBE, MULTILABELED NUCLEIC ACID PROBE, METHOD FOR PRODUCTION OF MULTILABELED NUCLEIC ACID PROBE, AND METHOD FOR DETECTION OF TARGET NUCLEIC ACID | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2011-08-04 | — | — | US | disclosed |
| EP-2301946-A1 | NUCLEOSIDE TRIPHOSPHATE DERIVATIVE, NUCLEIC ACID PROBE, MULTILABELED NUCLEIC ACID PROBE, METHOD FOR PRODUCTION OF MULTILABELED NUCLEIC ACID PROBE, AND METHOD FOR DETECTION OF TARGET NUCLEIC ACID | Kyushu University, National University Corporation (JP) | 2011-03-30 | — | — | EP | disclosed |
| US-7217738-B2 | β2-adrenergic receptor agonists | THERAVANCE, INC. (US) | 2007-05-15 | — | — | US | disclosed |
| US-7217738-B2 | β2-adrenergic receptor agonists | THERAVANCE, INC. (US) | 2007-05-15 | — | — | US | disclosed |
| US-7211695-B2 | β2-adrenergic receptor agonists | THERAVANCE, INC. (US) | 2007-05-01 | — | — | US | disclosed |
| US-7179794-B2 | Multivalent macrolide antibiotics | THERAVANCE, INC. (US) | 2007-02-20 | — | — | US | disclosed |
| US-7179794-B2 | Multivalent macrolide antibiotics | THERAVANCE, INC. (US) | 2007-02-20 | — | — | US | disclosed |
| US-7173039-B2 | Protein kinase inhibitors | THERAVANCE, INC. (US) | 2007-02-06 | — | — | US | disclosed |
| US-7173039-B2 | Protein kinase inhibitors | THERAVANCE, INC. (US) | 2007-02-06 | — | — | US | disclosed |
| US-4436925-A | Addition compound of dipeptide derivative and amino acid derivative | TOYO SODA MANUFACTURING CO., LTD. (JP) | 1984-03-13 | — | — | US | disclosed |
| US-4256836-A | REACTING AN N-SUBSTITUTED MONOAMINODICARBOXYLIC ACID WITH AN AMINO CARBOXYLIC ACID ESTER | TOYO SODA MANUFACTURING CO. LTD. (JP) | 1981-03-17 | — | — | US | disclosed |
| US-4165311-A | Addition compound of dipeptide derivative and amino acid derivative | TOYO SODA MANUFACTURING CO. LTD. (JP) | 1979-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110189671-A1 | NUCLEOSIDE TRIPHOSPHATE DERIVATIVE, NUCLEIC ACID PROBE, MULTILABELED NUCLEIC ACID PROBE, METHOD FOR PRODUCTION OF MULTILABELED NUCLEIC ACID PROBE, AND METHOD FOR DETECTION OF TARGET NUCLEIC ACID | DNTT, DTYMK, TYMP | MME 3128/4885ECE1 3117/4885NAALAD2 310/4885 |
| US-20160251450-A1 | PROTEIN-POLYMER COMPLEX, TGase SUBSTRATE-CONTAINING POLYMER, TGase SUBSTRATE-CONTAINING MONOMER, METHOD FOR PRODUCING PROTEIN-POLYMER COMPLEX, AND METHOD FOR IMPROVING PROTEIN FUNCTION AT SOLID-LIQUID INTERFACE OR IN VICINITY OF SOLID-LIQUID INTERFACE | GLUL, MAX, QPCTL | MME 2611/4885ECE1 1372/4885NAALAD2 83/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.