Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NAMPT | P43490 | 3/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31198112 | 0.91 | ESR2 (0.57) | HDAC1NR1H2ESR2DDB1CRBN | |
| SCHEMBL23727210 | 0.83 | HDAC1 (0.47) | HDAC1NR1H2ESR2DDB1CRBN | |
| SCHEMBL29835125 | 0.83 | HDAC1 (0.47) | HDAC1NR1H2ESR2DDB1CRBN | |
| SCHEMBL24182517 | 0.81 | HDAC1 (0.46) | HDAC1NR1H2ESR2DDB1CRBN | |
| SCHEMBL31447592 | 0.80 | NR1H2 (0.54) | HDAC1NR1H2ESR2DDB1CRBN | |
| SCHEMBL17221201 | 0.80 | HDAC1 (0.49) | HDAC1NR1H2ESR2DDB1CRBN | |
| SCHEMBL24761584 | 0.79 | ABHD6 (0.50) | HDAC1NR1H2ESR2DDB1CRBN | |
| SCHEMBL16417177 | 0.79 | HDAC1 (0.48) | HDAC1NR1H2ESR2DDB1CRBN | |
| SCHEMBL19358065 | 0.78 | HDAC1 (0.51) | HDAC1NR1H2ESR2DDB1CRBN | |
| SCHEMBL23727968 | 0.78 | HDAC1 (0.47) | HDAC1NR1H2ESR2DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109456324-B | Isoindoline or isoquinoline compounds, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2022-04-22 | — | — | CN | disclosed |