Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.42 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9381488 | 0.89 | CA1 (0.55) | CA1CA2KDM4EL3MBTL1MAPT | |
| SCHEMBL9381486 | 0.89 | CA1 (0.55) | CA1CA2KDM4EL3MBTL1MAPT | |
| SCHEMBL11409755 | 0.87 | SLC6A4 (0.52) | CA1CA2PTGS2KDM4EL3MBTL1 | |
| SCHEMBL11409757 | 0.87 | SLC6A4 (0.52) | CA1CA2PTGS2KDM4EL3MBTL1 | |
| SCHEMBL28740160 | 0.87 | SLC6A4 (0.52) | CA1CA2PTGS2KDM4EL3MBTL1 | |
| SCHEMBL11409699 | 0.85 | MAPT (0.48) | CA1CA2PTGS2KDM4EL3MBTL1 | |
| SCHEMBL11411274 | 0.83 | PTGS2 (0.49) | CA1CA2PTGS2KDM4EL3MBTL1 | |
| SCHEMBL11415378 | 0.83 | PTGS2 (0.50) | CA1CA2PTGS2KDM4EL3MBTL1 | |
| SCHEMBL11415375 | 0.83 | PTGS2 (0.50) | CA1CA2PTGS2KDM4EL3MBTL1 | |
| SCHEMBL11119514 | 0.82 | CA1 (0.49) | CA1CA2KDM4EL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114539124-B | Method for enantioselectively synthesizing N, 3-disubstituted-1-isoindolinone compound | 大连大学 | 2023-07-21 | — | — | CN | disclosed |
| CN-114394926-B | High-yield synthesis method of N, 3-disubstituted-1-isoindolinone compound | 大连大学 | 2023-06-27 | — | — | CN | disclosed |
| CN-114539124-A | Method for enantioselectively synthesizing N, 3-disubstituted-1-isoindolinone compound | 大连大学 | 2022-05-27 | — | — | CN | disclosed |
| CN-114394926-A | High-yield synthesis method of N, 3-disubstituted-1-isoindolinone compounds | 大连大学 | 2022-04-26 | — | — | CN | disclosed |