SCHEMBL28740076

SCHEMBL28740076

C=CCOC(=O)c1ccc(C(F)(F)F)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 1/20 0.57
CYP3A4 P08684 1/20 0.50
CES2 O00748 1/20 0.48
CES1 P23141 1/20 0.48
LMNA P02545 2/20 0.46
RAB9A P51151 2/20 0.46
MAPK1 P28482 1/20 0.46
PTPN1 P18031 2/20 0.46
GSK3B P49841 1/20 0.46
TRPV1 Q8NER1 1/20 0.44
ALDH1A1 P00352 2/20 0.44
NPC1 O15118 1/20 0.44
MAPT P10636 1/20 0.44
HTT P42858 1/20 0.44
TSHR P16473 1/20 0.44
HSD17B10 Q99714 1/20 0.44
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
RECQL P46063 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL175786 0.86 SNCA (0.67) SNCACYP3A4LMNAALDH1A1TSHR
SCHEMBL2207308 0.83 SNCA (0.54) SNCACYP3A4CES1TRPV1ALDH1A1
SCHEMBL9419972 0.83 SNCA (0.54) SNCACYP3A4LMNARAB9AMAPK1
SCHEMBL14780526 0.83 CES2 (0.48) SNCACYP3A4CES2LMNARAB9A
SCHEMBL14780442 0.83 CES2 (0.56) CYP3A4CES2LMNARAB9AMAPK1
SCHEMBL548224 0.82 SNCA (0.52) SNCACYP3A4LMNARAB9AMAPK1
SCHEMBL10980639 0.81 CES2 (0.53) CES2CES1LMNARAB9AMAPK1
SCHEMBL2834698 0.81 SNCA (0.58) SNCACYP3A4CES2CES1LMNA
SCHEMBL17386391 0.80 SNCA (0.61) SNCACYP3A4LMNAALDH1A1TSHR
SCHEMBL461801 0.80 SNCA (0.61) SNCACYP3A4LMNAALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114409538-B Allyl benzoate compound and preparation method thereof 湖北工业大学 2023-09-26 CN disclosed
CN-114409538-A Allyl benzoate compound and preparation method thereof 湖北工业大学 2022-04-29 CN disclosed