Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 6/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26487693 | 0.90 | ADORA3 (0.64) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL28740326 | 0.89 | NT5E (0.72) | NT5EADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL26487692 | 0.88 | ADORA3 (0.60) | NT5EADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL28740143 | 0.87 | NT5E (0.57) | NT5EADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL28740105 | 0.87 | NT5E (0.75) | NT5EADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL28740041 | 0.85 | NT5E (0.72) | NT5EADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL19100517 | 0.84 | NT5E (0.83) | NT5E | |
| SCHEMBL28740153 | 0.84 | NT5E (0.57) | NT5EADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL19799156 | 0.83 | ADORA3 (0.79) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL12192981 | 0.83 | ADORA3 (0.79) | ADORA3ADORA2AADORA2BADORA1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114395005-A | Modulators of extracellular 5' -nucleotidase and uses thereof | 艾库斯生物科学有限公司 | 2022-04-26 | — | — | CN | disclosed |