Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 7/20 | 0.45 |
| ▸ | NOS3 | P29474 | 2/20 | 0.43 |
| ▸ | NOS1 | P29475 | 2/20 | 0.43 |
| ▸ | NOS2 | P35228 | 2/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.41 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31324783 | 0.83 | NOS3 (0.56) | KIF11NOS3NOS1NOS2ALPI | |
| SCHEMBL24773894 | 0.83 | TSHR (0.46) | SLC6A2SLC6A4SLC6A3POLBKMT2A | |
| SCHEMBL28741535 | 0.83 | NOS3 (0.56) | KIF11NOS3NOS1NOS2ALPI | |
| SCHEMBL22445207 | 0.83 | LPAR1 (0.43) | KIF11SLC6A2SLC6A4SLC6A3LTA4H | |
| SCHEMBL5322254 | 0.80 | SLC1A5 (0.53) | KIF11NOS3NOS1NOS2ALPI | |
| SCHEMBL8819746 | 0.80 | SLC1A5 (0.53) | KIF11NOS3NOS1NOS2ALPI | |
| SCHEMBL30963028 | 0.80 | SLC1A5 (0.53) | KIF11NOS3NOS1NOS2ALPI | |
| SCHEMBL8819750 | 0.80 | SLC1A5 (0.53) | KIF11NOS3NOS1NOS2ALPI | |
| SCHEMBL31370243 | 0.78 | TAAR1 (0.50) | KIF11NOS3NOS1NOS2ALPI | |
| Homophenylalanine SCHEMBL4231539 | 0.78 | ALPI (0.56) | KIF11ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113692401-A | Process for producing aromatic amino acid derivative | 中外制药株式会社 | 2021-11-23 | — | — | CN | disclosed |