Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 2/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.35 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | PRKAB2 | O43741 | 4/20 | 0.34 |
| ▸ | PRKAG1 | P54619 | 4/20 | 0.34 |
| ▸ | PRKAA2 | P54646 | 4/20 | 0.34 |
| ▸ | PRKAA1 | Q13131 | 4/20 | 0.34 |
| ▸ | PRKAG3 | Q9UGI9 | 4/20 | 0.34 |
| ▸ | PRKAG2 | Q9UGJ0 | 4/20 | 0.34 |
| ▸ | PRKAB1 | Q9Y478 | 4/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29669962 | 1.00 | MAPK8 (0.46) | MAPK8MAPK9KCNH2IDH1MKNK1 | |
| SCHEMBL24288138 | 0.69 | MAPK8 (0.47) | MAPK8MAPK9KCNH2IDH1MKNK1 | |
| SCHEMBL28742102 | 0.69 | CYP19A1 (0.35) | — | |
| SCHEMBL29628823 | 0.69 | CYP19A1 (0.35) | — | |
| SCHEMBL29669987 | 0.68 | PRKAB2 (0.63) | MAPK1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL28742100 | 0.68 | PRKAB2 (0.63) | MAPK1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL28774081 | 0.67 | IGF1R (0.45) | — | |
| SCHEMBL29628901 | 0.67 | CYP19A1 (0.34) | — | |
| SCHEMBL17151392 | 0.67 | MKNK1 (0.55) | MAPK8MAPK9IDH1MKNK1MKNK2 | |
| SCHEMBL28774077 | 0.67 | CYP19A1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114539234-A | Synthesis method and application of C5-2-fatty amino pyrimidine azole compound | 深圳湾实验室 | 2022-05-27 | — | — | CN | disclosed |