Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAT2A | P31153 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27518959 | 0.78 | ALDH1A1 (0.42) | ALDH1A1KDM4EARKMT2ANPSR1 | |
| SCHEMBL27543740 | 0.74 | AR (0.36) | ALDH1A1KDM4EARKMT2ANPSR1 | |
| SCHEMBL27543821 | 0.74 | AR (0.36) | ALDH1A1KDM4EARKMT2ANPSR1 | |
| SCHEMBL27543770 | 0.74 | PRMT5 (0.38) | ALDH1A1KDM4EARKMT2ANPSR1 | |
| SCHEMBL27518965 | 0.74 | ALDH1A1 (0.34) | ALDH1A1KDM4EARKMT2ANPSR1 | |
| SCHEMBL27543777 | 0.74 | AR (0.36) | ALDH1A1ARKMT2AMEN1MAPT | |
| SCHEMBL27543731 | 0.73 | PRMT5 (0.37) | ALDH1A1ARKMT2AGAAATM | |
| SCHEMBL27544757 | 0.73 | AR (0.38) | ALDH1A1ARSMN1; SMN2 | |
| SCHEMBL27518208 | 0.71 | KDM4E (0.39) | ALDH1A1KDM4EARKMT2AMEN1 | |
| SCHEMBL27544750 | 0.70 | MAP2K1 (0.32) | ALDH1A1ARMAT2ACA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1382124-A | Bicyclic androgen and progesterone receptor modulating compounds and methods | LIGAND PHARM INC (US) | 2002-11-27 | — | — | CN | claimed |
| CN-100384823-C | Bicyclic androgen and progesterone receptor modulator compounds and methods | LIGAND PHARM INC (US) | 2008-04-30 | — | — | CN | disclosed |
| CN-101029042-A | Bicyclic androgen and progesterone receptor modulator compounds and methods | LIGAND PHARM INC (US) | 2007-09-05 | — | — | CN | disclosed |
| CN-1262540-C | Bicyclic androgen and progesterone receptor modulating compounds and methods | LIGAND PHARM INC (US) | 2006-07-05 | — | — | CN | disclosed |
| CN-1775759-A | Bicyclic androgen and progesterone receptor modulator compounds and methods | LIGAND PHARM INC (US) | 2006-05-24 | — | — | CN | disclosed |
| CN-1382124-A | Bicyclic androgen and progesterone receptor modulating compounds and methods | LIGAND PHARM INC (US) | 2002-11-27 | — | — | CN | disclosed |