Methylamine

Methylamine

SCHEMBL28742976

CC(C)c1nccs1.CN

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
TSHR P16473 1/20 0.44
NOS1 P29475 1/20 0.44
HSD17B10 Q99714 1/20 0.44
KDM4E B2RXH2 2/20 0.38
LMNA P02545 1/20 0.38
MAPKAPK2 P49137 1/20 0.37
FBP1 P09467 2/20 0.36
PDK1 Q15118 1/20 0.36
ADORA3 P0DMS8 1/20 0.35
ADORA2A P29274 1/20 0.35
ADORA2B P29275 1/20 0.35
ADORA1 P30542 1/20 0.35
HRH1 P35367 3/20 0.33
CYP2D6 P10635 2/20 0.33
KCNH2 Q12809 2/20 0.33
CHRM1 P11229 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL557653 0.95
Methyl Alcohol SCHEMBL27817336 0.91 ALDH1A1 (0.40) ALDH1A1TSHRNOS1HSD17B10KDM4E
SCHEMBL267683 0.81
SCHEMBL3342146 0.81
SCHEMBL4489846 0.81
Hydrochloric Acid SCHEMBL3508344 0.79
SCHEMBL12261831 0.77 ALDH1A1 (0.41) ALDH1A1TSHRNOS1HSD17B10KDM4E
SCHEMBL27783363 0.77 ALDH1A1 (0.55) ALDH1A1TSHRKDM4ELMNAMAPKAPK2
SCHEMBL19267359 0.76
SCHEMBL21037832 0.76 ALDH1A1 (0.39) ALDH1A1TSHRNOS1HSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108218808-A A kind of preparation method of Ritonavir 盐城迪赛诺制药有限公司 2018-06-29 CN disclosed
CN-1247554-C Process for synthesizing ritonavir UNIV XIAMEN (CN) 2006-03-29 CN disclosed