Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | PDE2A | O00408 | 3/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | MPL | P40238 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28743563 | 1.00 | IDO1 (0.50) | IDO1DAOSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL1426705 | 0.79 | IDO1 (0.53) | IDO1DAOSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL1117948 | 0.76 | IDO1 (0.58) | IDO1DAOSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL27634838 | 0.76 | IDO1 (0.58) | IDO1DAOSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL7977134 | 0.76 | IDO1 (0.62) | IDO1DAOSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL17864260 | 0.76 | IDO1 (0.58) | IDO1DAOSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL5426147 | 0.74 | IDO1 (0.61) | IDO1DAOSLC6A4SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL4496729 | 0.73 | IDO1 (0.64) | IDO1DAOSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL5440588 | 0.73 | IDO1 (0.54) | IDO1DAOSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL28743578 | 0.72 | IDO1 (0.48) | IDO1KDM4ETAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108101826-B | Indole-substituted alkylamine compound and application thereof | 华东理工大学 | 2022-05-10 | — | — | CN | disclosed |